- Regulation of fibronectin gene expression by cyclic AMP and phorbol myristate acetate in HT-1080 human fibrosarcoma cells
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Lee BH, Park RW, Kim IS
- KMID: 755015
- Exp Mol Med.
- 1998 Dec;30(4):240-245.
We studied the regulation of fibronectin (FN) gene expression by cAMP and phorbol-12-myristate-13-acetate (PMA) in HT-1080 human fibrosarcoma cells. Dibutyryl cAMP increased FN synthesis and mRNA levels, while PMA inhibited... -
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- Relaxin Modulates the Expression of MMPs and TIMPs in Fibroblasts of Patients with Carpal Tunnel Syndrome
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Kang YM, Lee HM, Moon SH, Kang H, Choi YR
- KMID: 2427132
- Yonsei Med J.
- 2017 Mar;58(2):415-422.
- doi: 10.3349/ymj.2017.58.2.415
PURPOSE: The aim of this study was to investigate the anti-fibrotic effect of relaxin in subsynovial fibroblasts activated by transforming growth factor beta (TGF-β). MATERIALS AND METHODS: To test the anti-fibrotic... -
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- Partial Purification and Properties of a Cysteine Protease from Citrus Red Mite Panonychus citri
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Hong SC, Her KH, Kim HU, Lee J, Lee SP, Chung YB
- KMID: 1715683
- Korean J Parasitol.
- 2014 Feb;52(1):117-120.
- doi: 10.3347/kjp.2014.52.1.117
Several studies have reported that the citrus red mites Panonychus citri were an important allergen of citrus-cultivating farmers in Jeju Island. The aim of the present study was to purify... -
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- The Genetically Modified Polysialylated Form of Neural Cell Adhesion Molecule-Positive Cells for Potential Treatment of X-Linked Adrenoleukodystrophy
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Jang J, Kim HS, Kang JW, Kang HC
- KMID: 1776946
- Yonsei Med J.
- 2013 Jan;54(1):246-252.
- doi: 10.3349/ymj.2013.54.1.246
PURPOSE: Cell transplantation of myelin-producing exogenous cells is being extensively explored as a means of remyelinating axons in X-linked adrenoleukodystrophy. We determined whether 3,3',5-Triiodo-L-thyronine (T3) overexpresses the ABCD2 gene in... -
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- Purification of a 68-kDa cysteine proteinase from crude extract of Pneumocystis carinii
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Choi MH, Chung BS, Chung YB, Yu JR, Cho SR, Hong ST
- KMID: 1720318
- Korean J Parasitol.
- 2000 Sep;38(3):159-166.
- doi: 10.3347/kjp.2000.38.3.159
The present study intended to verify activities of cysteine proteinase of Pneumocystis carinii from rats and to purify the enzyme. In order to exclude the contamination of host-derived enzymes, concentrates... -
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- Rapamycin Inhibits Transforming Growth Factor beta1-Induced Fibrogenesis in Primary Human Lung Fibroblasts
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Gao Y, Xu X, Ding K, Liang Y, Jiang D, Dai H
- KMID: 1503908
- Yonsei Med J.
- 2013 Mar;54(2):437-444.
- doi: 10.3349/ymj.2013.54.2.437
PURPOSE: The present study was designed to determine whether rapamycin could inhibit transforming growth factor beta1 (TGF-beta1)-induced fibrogenesis in primary lung fibroblasts, and whether the effect of inhibition would occur... -
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- Induction of fibronectin gene expression by inhibitors of protein phosphatase type 2B in normal and transformed fibroblasts
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Rhew JH, Shin YA, Lee BH, Park RW, Kim IS
- KMID: 1029934
- Exp Mol Med.
- 1999 Jun;31(2):71-75.
Two intracellular signal pathways mediated by cAMP and protein kinase C (PKC) were involved in the regulation of FN gene expression (Lee et al., Exp. Mol. Med. 30: 240, 1998). In this... -
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