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KR-31831, a new synthetic anti-ischemic agent, inhibits in vivo and in vitro angiogenesis

Yi EY, Park SY, Song HS, Son MJ, Yi KY, Yoo SE, Kim YJ

  • KMID: 1098084
  • Exp Mol Med.
  • 2006 Oct;38(5):502-508.
Angiogenesis is considered to be an integral process to the growth and spread of solid tumors. Anti-angiogenesis therapy recently has been found to be one of the most promising anti-cancer...
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Computational Analysis of Tumor Angiogenesis Patterns Using a Two-dimensional Model

Shim EB, Kwon YG, Ko HJ

Tumor angiogenesis was simulated using a two-dimensional computational model. The equation that governed angiogenesis comprised a tumor angiogenesis factor (TAF) conservation equation in time and space, which was solved numerically...
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Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro

Park HY, Kwon HM, Lim HJ, Hong BK, Lee JY, Park BE, Jang YS, Cho SY, Kim HS

  • KMID: 1085746
  • Exp Mol Med.
  • 2001 Jun;33(2):95-102.
Leptin, the product of ob gene, is an endocrine hormone that regulates adipose tissue mass. Recently, leptin has been found to generate a growth signal involving a tyrosine kinase-dependent intracellular...
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