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What is fetal programming?: a lifetime health is under the control of in utero health

Kwon EJ, Kim YJ

The “Barker hypothesis” postulates that a number of organ structures and associated functions undergo programming during embryonic and fetal life, which determines the set point of physiological and metabolic responses...
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A developmental perspective on the origins of obesity and metabolic syndrome

Choi YS, Hwang IT

Metabolic syndrome comprises central obesity, dyslipidemia, hypertension, glucose intolerance, and insulin resistance. Children sometimes develop metabolic syndrome, and it is strongly associated with the same syndrome in adulthood. Recently, there...
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Mitochondrial Dysfunction and Insulin Resistance: The Contribution of Dioxin-Like Substances

Lee HK

Persistent organic pollutants (POPs) are known to cause mitochondrial dysfunction and this in turn is linked to insulin resistance, a key biochemical abnormality underlying the metabolic syndrome. To establish the...
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