- Pan-cancer Analysis of Tumor Mutational Burden and Homologous Recombination DNA Damage Repair Using Targeted Next-Generation Sequencing
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Wang HY, Deng L, Li YQ, Zhang X, Long YK, Zhang X, Feng YF, He Y, Tang T, Yang XH, Wang F
- KMID: 2521573
- Cancer Res Treat.
- 2021 Oct;53(4):973-982.
- doi: 10.4143/crt.2020.798
Purpose Current variability in methods for tumor mutational burden (TMB) estimation and reporting demonstrates the urgent need for a homogeneous TMB assessment approach. Here, we compared TMB distributions in different... -
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- Intravenous Tenecteplase for Acute Ischemic Stroke Within 4.5–24 Hours of Onset (ROSE-TNK): A Phase 2, Randomized, Multicenter Study
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Wang L, Dai YJ, Cui Y, Zhang H, Jiang CH, Duan YJ, Zhao Y, Feng YF, Geng SM, Zhang ZH, Lu J, Zhang P, Zhao LW, Zhao H, Ma YT, Song CG, Zhang Y, Chen HS
- KMID: 2546438
- J Stroke.
- 2023 Sep;25(3):371-377.
- doi: 10.5853/jos.2023.00668
Background and Purpose Intravenous tenecteplase (TNK) efficacy has not been well demonstrated in acute ischemic stroke (AIS) beyond 4.5 hours after onset. This study aimed to determine the effect of... -
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