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Diffusion MRI With High to Ultrahigh b-Values: How It Will Benefit the Discovery of Brain Microstructure and Pathological Changes

Wongkornchaovalit P, Feng M, He H, Zhong J

Diffusion MRI (dMRI) has been widely utilized to probe the random motion of water molecules in tissues. In a dMRI acquisition protocol, diffusion weighting or b-value is one of the...
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The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway

Cheng Z, Zhang Q, Yin A, Feng M, Li H, Liu H, Li Y, Qian L

In a previous study, we screened thousands of long non-coding RNAs (lncRNAs) to assess their potential relationship with congenital heart disease (CHD). In this study, uc.4 attracted our attention because...
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The SingHealth Perioperative and Anesthesia Subject Area Registry (PASAR), a large-scale perioperative data mart and registry

Abdullah HR, Lim DYZ, Ke Y, Salim NNM, Lan X, Dong Y, Feng M

Background: To enhance perioperative outcomes, a perioperative registry that integrates high-quality real-world data throughout the perioperative period is essential. Singapore General Hospital established the Perioperative and Anesthesia Subject Area Registry...
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Genistein Improves the Major Depression through Suppressing the Expression of miR-221/222 by Targeting Connexin 43

Shen F, Huang WL, Xing BP, Fang X, Feng M, Jiang CM

OBJECTIVE: Recent studies have indicated the possibility that genistein may improve depression via regulating the expression of miR-221/222. This study is to explore whether genistein could improve depression by altering...
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Insulin Resistance Is an Important Risk Factor for Cognitive Impairment in Elderly Patients with Primary Hypertension

Ma L, Feng M, Qian Y, Yang W, Liu J, Han R, Zhu H, Li Y

PURPOSE: Insulin resistance plays a role in the development of dementia and hypertension. We investigated a possible relationship between cognitive impairment and insulin resistance in elderly Chinese patients with primary...
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Sputum Autoantibodies Are More Relevant in Autoimmune Responses in Asthma than Are Serum Autoantibodies

Qin R, Long F, Xiao X, Xiao J, Zheng Z, Feng M, Huang R, Peng T, Li J

PURPOSE: The data on the differences between sputum autoantibodies (Sp-Abs) and serum autoantibodies (Se-Abs) in reflection of autoimmune responses to lungs is still lacking. METHODS: Ten types of Abs were investigated...
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