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Overview of Clinical Experience in the Treatment of Peptic Ulcer with Famotidine

Park CK, Ju SU, Rim KS

  • KMID: 2243890
  • Korean J Gastrointest Endosc.
  • 1987 Nov;7(1):27-30.
The aim of the investigation was to study the efficacy and safety of Famotidine (Gaster), a new, potent, histamine H-receptor antagonist. The Famotidine (40 mg p.o.h.s) was administered to 22...
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A Case of Famotidine-associated Delirium

Lee KM, Kim SW, Lee DS, Song HJ, Yang YS, Chae HS, Ahn BM, Chung IS, Park DH

  • KMID: 1598384
  • Korean J Gastroenterol.
  • 2001 Feb;37(2):128-131.
The use of histamine (H2)-receptor blockers has been associated with central nervous system (CNS) toxicities manifesting as delirium, mental confusion, dizziness, and hallucination. Elderly patients with renal or hepatic dysfunction...
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Three Cases of Hepatitis Related to the Use of Famotidine and Ranitidine

Sohn JH, Sohn YW, Jeon YC, Han DS, Hahm JS, Choi HS, Park KN, Kee CS

  • KMID: 2143308
  • Korean J Hepatol.
  • 1998 Jun;4(2):194-199.
H2-receptor blockers are widely used for therapy of peptic ulcer disease and gastroesophageal reflux disease. H2-receptor blockers infrequently cause adverse hepatic effects, and when they occur they are usually asymptomatic. There are...
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Effect of Famotidine Premedication on Volume and Acidity of Gastric Contents during General Anesthesia

Bae SB, Kim HJ, Yum KW

BACKGROUND: Severity of aspiration pneumonitis is associated with acidity and volume of aspirated gastric contents. Volume and acidity of gastric contents are influenced by food, drugs, and patient factors. ...
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Famotidine versus Pantoprazole for the Prevention of Delayed Bleeding and Healing of Iatrogenic Ulcers after Endoscopic Mucosal Resection

Hwang HI, Park CH, Yum SM, Lee S, Lee WS, Kim HS, Choi SK, Rew JS

  • KMID: 2304792
  • Korean J Gastrointest Endosc.
  • 2008 Sep;37(3):179-184.
BACKGROUND/AIMS: Endoscopic mucosal resection (EMR) currently serves as the minimally invasive treatment of choice for early gastric cancer and premalignant lesions of the stomach. There have been few studies addressing...
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A Comparison of the Effects of Cimetidine, Ranitidine and Famotidine as Premedication on Gastric Volume and pH

Lee WY, Kim HJ, Yum KW

BACKGROUND: Aspiration pneumonitis is one of the most severe anesthetic complications. The severity of this complication is associated with the acidic nature of aspirated gastric juice. H2 receptor antagonists inhibit...
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Famotidine-induced reversal of meperidine-related serotonin syndrome: a case report

Joe S, Kim E, Park J, Lee D, Son J, Kim H

Serotonin syndrome is an unexpected fatal adverse event related to serotonergic medication. This case report is the first report describing the possible treatment effect of famotidine on serotonin syndrome. Furthermore,...
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The Effect of Famotidine on Lowering Gastric Acidity in Gastric Carcinoma Patients

Park SH, Lee SW, Kim DS, Ryu SJ, Kim KH, Chang TH, Kim SH

BACKGROUND: To identify the gastric pH of gastric carcinoma patients after more than 8 hours of fasting and ascertain the antisecretory effects of H2-receptor antagonists, the gastric volume and pH...
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The Effects of Preanesthetic Low Dose Famotidine on Gastric pH and Volume in Children

Lee SW, Kim DS, Park SH, Ryu SJ, Kim KH, Jang TH, Kim SH

BACKGROUND: Children undergoing general anesthesia are at increased risk of aspiration pneumonia. Cimetidine and ranitidine, specific histamine (H2-receptor) antagonists, markedly reduce the acidity and volume of gastric content when given...
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A Prospective Randomized Trial of Either Famotidine or Pantoprazole for the Prevention of Bleeding after Endoscopic Submucosal Dissection

Jeong HK, Park CH, Jun CH, Lee GH, Kim HI, Kim HS, Choi SK, Rew JS

Endoscopic submucosal dissection (ESD) has been reported to have a higher bleeding rate than conventional methods. However, there are few reports on whether a proton pump inhibitor or a histamine2-receptor...
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Effect of H2-receptor Blockers on Antagonism of Vecuronium Neuromuscular Blockade

Lee SK, Hwang KH, Kim SY

Recently, several studies have shown that the H2-receptor blockers can cause inhibition of cholinesstrase and neuromuscular blockade which suggest involvement of ion-chennel block in relatively large experimental dose. We investigated...
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Usefulness of Appropriate Management of Ulcer with FORREST II Bleeding Activity: A Prospective, Randomized Study

Kim SE, Yi SY, Shin JE, Ju MS, Chun JH, Lee KE

OBJECTIVES: This study is to compare the clinical and cost effectiveness of various pharmacologic therapies with of without endoscopic procedure in the Forrest II ulcer. METHODS: Between May 2001 and June...
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Rebamipide May Be Comparable to H2 Receptor Antagonist in Healing Iatrogenic Gastric Ulcers Created by Endoscopic Mucosal Resection: A Prospective Randomized Pilot Study

Kim YJ, Cheon JH, Lee SK, Kim JH, Lee YC

Endoscopic mucosal resection (EMR) results in the formation of iatrogenic gastric ulcers and the optimal treatments for such ulcers are still unclear. We aimed to evaluate the efficacy of rebamipide...
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The Effect of H2-receptor Blockers on the Duration of Action of Succinylcholine and Vecuronium

Kim IH, Ok SY, Hwang KH, Kim SY

Cimetidine, and H2-receptor blocker, is associated with a direct inhibition of liver microsomal enzymes and a decrease in liver blood flow which results in a variety of clinically significant drug...
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A Case of Ranitidine-Induced Anaphylaxis

  • KMID: 2146027
  • Korean J Asthma Allergy Clin Immunol.
  • 2010 Jun;30(2):140-143.
Ranitidine is a widely used H2 receptor antagonist that is usually well tolerated by patients. An anaphylactic reaction to ranitidine is rare. Here, we report a case of ranitidine-induced anaphylaxis....
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Two Cases of H2-Receptor Antagonist Hypersensitivity and Cross-Reactivity

Song WJ, Kim MH, Lee SM, Kwon YE, Kim SH, Cho SH, Min KU, Kim YY, Chang YS

H2-receptor antagonists, such as cimetidine, ranitidine and famotidine, are some of the most commonly prescribed medications for gastric acid-related disorders. These compounds are generally well-tolerated and anaphylactic reactions to them...
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Effects of Histamine-2 Receptor Antagonists and Proton Pump Inhibitors on the Rate of Gastric Emptying: A Crossover Study Using a Continuous Real-Time 13C Breath Test (BreathID System)

Nonaka T, Kessoku T, Ogawa Y, Imajyo K, Yanagisawa S, Shiba T, Sakaguchi , Atsukawa K, Takahashi , Sekino Y, Sakai E, Uchiyama T, Iida H, Hosono K, Endo H, Sakamoto Y, Fujita K, Yoneda M, Koide T, Takahashi , Tokoro C, Abe Y, Gotoh E, Maeda S, Nakajima A, Inamori M

  • KMID: 2325819
  • J Neurogastroenterol Motil.
  • 2011 Jul;17(3):287-293.
BACKGROUND/AIMS: The effects of Histamine-2 receptor antagonists and proton pump inhibitors on the gastrointestinal motility have not yet been sufficiently investigated. The aim of this study was to determine the...
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H2 Receptor Antagonists and Gastric Cancer in the Elderly: A Nested Case-Control Study

Kim Y, Heo DS, Lee SM, Youn KE, Koo HW, Bae JM, Park BJ

  • KMID: 2283263
  • Korean J Prev Med.
  • 2002 Aug;35(3):245-254.
OBJECTIVE: To test if the intake of H2 receptor antagonists (H2-RAs) increases the risk of gastric cancer in the elderly. METHODS: The source population for this study was drawn from the...
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