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Differential Cellular Tropism of Lentivirus and Adeno-Associated Virus in the Brain of Cynomolgus Monkey

An H, Cho DW, Lee SE, Yang YS, Han SC, Lee CJ

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High Levels of IL-8 and MCP-1 in Cerebrospinal Fluid of COVID-19 Patients with Cerebrovascular Disease

Guartazaca-Guerrero S, Rodríguez-Morales J, Rizo-Téllez SA, Solleiro-Villavicencio H, Hernández-Valencia AF, Carrillo-Ruiz JD, Escobedo G, Méndez-García LA

  • KMID: 2517478
  • Exp Neurobiol.
  • 2021 Jun;30(3):256-261.
  • doi: 10.5607/en21009
The coronavirus family has tropism for the Central Nervous System (CNS), however, there is no solid evidence demonstrating that the neurological effects of COVID-19 result from direct viral infection or...
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Long Noncoding RNA PVT1 Promotes Stemness and Temozolomide Resistance through miR-365/ELF4/SOX2 Axis in Glioma

Gong R, Li ZQ, Fu K, Ma C, Wang W, Chen JC

  • KMID: 2517477
  • Exp Neurobiol.
  • 2021 Jun;30(3):244-255.
  • doi: 10.5607/en20060
Long non-coding RNA (lncRNA) are a class of non-coding RNAs demonstrated to play pivotal roles in regulating tumor progression. Therefore, deciphering the regulatory role of lncRNA in the development of...
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Ciliogenesis is Not Directly Regulated by LRRK2 Kinase Activity in Neurons

Kim H, Sim H, Lee JE, Seo MK, Lim J, Bang Y, Nam D, Lee SY, Chung SK, Choi HJ, Park SW, Son I, Kim J, Seol W

  • KMID: 2517476
  • Exp Neurobiol.
  • 2021 Jun;30(3):232-243.
  • doi: 10.5607/en21003
Mutations in the Leucine-rich repeat kinase 2 (LRRK2 ) gene are the most prevalent cause of familial Parkinson’s disease (PD). The increase in LRRK2 kinase activity observed in the pathogenic...
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Adenovirus-induced Reactive Astrogliosis Exacerbates the Pathology of Parkinson’s Disease

An H, Lee H, Yang S, Won W, Lee CJ, Nam MH

  • KMID: 2517475
  • Exp Neurobiol.
  • 2021 Jun;30(3):222-231.
  • doi: 10.5607/en21013
Parkinson’s disease (PD) is the most prevalent neurodegenerative motor disorder. While PD has been attributed to dopaminergic neuronal death in substantia nigra pars compacta (SNpc), accumulating lines of evidence have...
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Differential Proximity of Perisynaptic Astrocytic Best1 at the Excitatory and Inhibitory Tripartite Synapses in APP/PS1 and MAOB-KO Mice Revealed by Lattice Structured Illumination Microscopy

An H, Koh W, Kang S, Nam MH, Lee CJ

  • KMID: 2517474
  • Exp Neurobiol.
  • 2021 Jun;30(3):213-221.
  • doi: 10.5607/en21015
Bestrophin-1 (Best1) is a GABA- and glutamate-permeable, Ca 2+ -activated Cl - channel, which is mainly expressed in astrocytes and localized at the microdomain or perisynaptic junction of the tripartite...
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Cell Type-specific Knockout with Gli1-mediated Cre Recombination in the Developing Cerebellum

Choi JM, Acharya R, Marasini S, Narayan B, Lee KW, Hwang WS, Chang DY, Kim SS, Kim HS

  • KMID: 2517473
  • Exp Neurobiol.
  • 2021 Jun;30(3):203-212.
  • doi: 10.5607/en21017
The inducible Cre-loxP system provides a useful tool for inducing the selective deletion of genes that are essential for proper development and enables the study of gene functions in properly...
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