- Neuro-Behcet's Disease Presenting as Hypertrophic Pachymeningitis
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Yoon BN, Kim SJ, Lim MJ, Han JY, Lee KW, Sung JJ, Ha CK, Choi SH
- KMID: 2165562
- Exp Neurobiol.
- 2015 Sep;24(3):252-255.
- doi: 10.5607/en.2015.24.3.252
A 25-year-old man presented with blurred vision and chronic headache. His brain MRI revealed bilateral frontal pachymeningeal enhancement with leptomeningeal enhancement. The patient had experienced recurrent oral ulcer and had... -
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- Specific Expression of Aplysia Phosphodiesterase 4 in Bag Cells Revealed by in situ Hybridization Analysis
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Jang DJ, Kim HF, Sim JH, Lim CS, Kaang BK
- KMID: 2165561
- Exp Neurobiol.
- 2015 Sep;24(3):246-251.
- doi: 10.5607/en.2015.24.3.246
Phosphodiesterases (PDEs) play a key role in the regulation of cyclic adenosine monophosphate (cAMP), which in turn mediates various cellular functions including learning and memory. We previously cloned and characterized... -
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- The Unreliability of MTT Assay in the Cytotoxic Test of Primary Cultured Glioblastoma Cells
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Jo HY, Kim Y, Park HW, Moon HE, Bae S, Kim J, Kim DG, Paek SH
- KMID: 2165560
- Exp Neurobiol.
- 2015 Sep;24(3):235-245.
- doi: 10.5607/en.2015.24.3.235
MTT assay is commonly used to assess the cellular cytotoxicity caused by anticancer drugs in glioblastomas. However, there have been some reports insisting that MTT assay exhibited non-specific intracellular reduction... -
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- Modulation of SOD1 Subcellular Localization by Transfection with Wild- or Mutant-type SOD1 in Primary Neuron and Astrocyte Cultures from ALS Mice
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Lee DY, Jeon GS, Shim YM, Seong SY, Lee KW, Sung JJ
- KMID: 2165559
- Exp Neurobiol.
- 2015 Sep;24(3):226-234.
- doi: 10.5607/en.2015.24.3.226
Amyotrophic lateral sclerosis (ALS) is a fatal neurological disorder characterized by selective degeneration of motor neurons. Mutant superoxide dismutase 1 (SOD1) is often found as aggregates in the cytoplasm in... -
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- Control of Mitochondrial Dynamics by Fas-induced Caspase-8 Activation in Hippocampal Neurons
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Cho HM, Sun W
- KMID: 2165558
- Exp Neurobiol.
- 2015 Sep;24(3):219-225.
- doi: 10.5607/en.2015.24.3.219
Cells undergo apoptosis mainly via two pathways-the mitochondrial pathway and the cytosolic pathway. It has been well documented that activation of the mitochondrial pathway promotes mitochondrial fragmentation and inhibition of... -
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- Disinhibitory Action of Astrocytic GABA at the Perforant Path to Dentate Gyrus Granule Neuron Synapse Reverses to Inhibitory in Alzheimer's Disease Model
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Yarishkin , Lee J, Jo S, Hwang EM, Lee CJ
- KMID: 2165557
- Exp Neurobiol.
- 2015 Sep;24(3):211-218.
- doi: 10.5607/en.2015.24.3.211
Like neurons, astrocytes produce and release GABA to influence neuronal signaling. At the perforant path to dentate gyrus granule neuron synapse, GABA from astrocyte was found to be a strong... -
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- Membrane-Introduction Mass Spectrometry Analysis of Desflurane, Propofol and Fentanyl in Plasma and Cerebrospinal Fluid for Estimation BBB Properties
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Cherebillo VY, Elizarov A, Polegaev A
- KMID: 2165556
- Exp Neurobiol.
- 2015 Sep;24(3):206-210.
- doi: 10.5607/en.2015.24.3.206
A possibility to use the Membrane-Introduction Mass Spectrometry (MIMS) with membrane separator interface has evolved into a powerful method for measurement of anaesthetic agents absolute concentration in blood plasma and... -
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- Glucose Levels in Culture Medium Determine Cell Death Mode in MPP+-treated Dopaminergic Neuronal Cells
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Yoon SY, Oh YJ
- KMID: 2165555
- Exp Neurobiol.
- 2015 Sep;24(3):197-205.
- doi: 10.5607/en.2015.24.3.197
We previously demonstrated that 1-methyl-4-phenylpyridinium (MPP+) causes caspase-independent, non-apoptotic death of dopaminergic (DA) neuronal cells. Here, we specifically examined whether change of glucose concentration in culture medium may play a... -
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- Peripheral Biomarker Candidates of Posttraumatic Stress Disorder
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Kang HJ, Yoon S, Lyoo IK
- KMID: 2165554
- Exp Neurobiol.
- 2015 Sep;24(3):186-196.
- doi: 10.5607/en.2015.24.3.186
There is high variability in the manifestation of physical and mental health problems following exposure to trauma and disaster. Although most people may show a range of acute symptoms in... -
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- Roles of mTOR Signaling in Brain Development
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Lee DY
- KMID: 2165553
- Exp Neurobiol.
- 2015 Sep;24(3):177-185.
- doi: 10.5607/en.2015.24.3.177
mTOR is a serine/threonine kinase composed of multiple protein components. Intracellular signaling of mTOR complexes is involved in many of physiological functions including cell survival, proliferation and differentiation through the... -
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