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Erratum: A Method for Generating Mouse Model of Stroke: Evaluation of Parameters for Blood Flow, Behavior, and Survival

Park SY, Marasini S, Kim GH, Ku T, Choi C, Park MY, Kim EH, Lee YD, Suh-Kim H, Kim SS

We correct a typo in the title.
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Mitogen Activated Protein Kinase Family Proteins and c-jun Signaling in Injury-induced Schwann Cell Plasticity

Lee HJ, Shin YK, Park HT

Schwann cells (SCs) in the peripheral nerves myelinate axons during postnatal development to allow saltatory conduction of nerve impulses. Well-organized structures of myelin sheathes are maintained throughout life unless nerves...
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Lipocalin-2 Acts as a Neuroinflammatogen in Lipopolysaccharide-injected Mice

Jin M, Jang E, Suk K

Lipocalin-2 (LCN2) is a key mediator of various cellular processes. Recent studies have indicated that LCN2 also plays an important role in central nervous system (CNS) injuries and neurological diseases,...
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Isoliquiritigenin, a Chalcone Compound, Enhances Spontaneous Inhibitory Postsynaptic Response

Woo J, Cho S, Lee CJ

Isoliquiritigenin (ILTG) is a chalcone compound and shows various pharmacological properties, including antioxidant and anti-inflammatory activities. In recent study, we have reported a novel role of ILTG in sleep through...
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Calbindin-D28K Prevents Staurosporin-induced Bax Cleavage and Membrane Permeabilization

Choi WS, Oh YJ

Calbindin-D28K has been implicated in the regulation of neuronal cell death. Previously, we demonstrated that calbindin-D28K prevents staurosporine (STS)-induced caspase activation and subsequent apoptosis in a neuronal cell line. However,...
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Learning-dependent Changes in the Neuronal Correlates of Response Inhibition in the Prefrontal Cortex and Hippocampus

Lee I, Byeon JS

It has been suggested that the hippocampus and the prefrontal cortex (PFC) play key roles in representing contextual memory and utilizing contextual information for flexible response selection. During response selection,...
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Delayed and Prolonged Local Brain Hypothermia Combined with Decompressive Craniectomy: A Novel Therapeutic Strategy That Modulates Glial Dynamics

Kim JH, Yun SH, Jang KH, Park J, Han HS, Rhee D, Suk K

Hypothermia is considered a useful intervention for limiting pathophysiological changes after brain injury. Local hypothermia is a relatively safe and convenient intervention that circumvents many of the complications associated with...
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A Decade of Research on TLR2 Discovering Its Pivotal Role in Glial Activation and Neuroinflammation in Neurodegenerative Diseases

Hayward JH, Lee SJ

Toll-like receptors (TLRs) belong to a class of pattern recognition receptors that play an important role in host defense against pathogens. TLRs on innate immune cells recognize a wide variety...
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Suppression of miR-155 Expression in IFN-gamma-Treated Astrocytes and Microglia by DJ-1: A Possible Mechanism for Maintaining SOCS1 Expression

Kim JH, Jou I, Joe EH

Previously, we reported that DJ-1, encoded by a Parkinson's disease (PD)-associated gene, inhibits expression of proinflammatory mediators in interferon-gamma (IFN-gamma)-treated astrocytes and microglia through inhibition of STAT1 activation. Here, using...
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Dynamic Transcriptional Events in Distal Sural Nerve Revealed by Transcriptome Analysis

Hong YB, Jung SC, Lee J, Moon HS, Chung KW, Choi BO

Compared with biochemical information available about the diseases in the central nervous system, that for peripheral neuropathy is quite limited primarily due to the difficulties in obtaining samples. Characterization of...
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Naringin: A Protector of the Nigrostriatal Dopaminergic Projection

Jung UJ, Leem E, Kim SR

Parkinson's disease is the second most common neurodegenerative disorder characterized by the progressive degeneration of dopaminergic neurons and a biochemical reduction of striatal dopamine levels. Despite the lack of fully...
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