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Environmental-Genetic Interactions in the Pathogenesis of Parkinson's Disease

Tsuboi Y

To date, numerous case-control studies have shown the complexity of the pathogenesis of Parkinson's disease (PD). In terms of genetic factors, several susceptibility genes are known to contribute to the...
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Serotonin and Synaptic Transmission at Invertebrate Neuromuscular Junctions

Wu WH, Cooper RL

The serotonergic system in vertebrates and invertebrates has been a focus for over 50 years and will likely continue in the future. Recently, genomic analysis and discovery of alternative splicing...
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Messages from the Brain Connectivity Regarding Neural Correlates of Consciousness

Jin SH, Chung CK

Consciousness has become a legitimate theme of neuroscientific discourse over the last two decades. Neuroscientific investigation seeking neural correlates of consciousness (NCC) has ranged from the neuronal level to the...
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Sensory Axon Regeneration: A Review from an in vivo Imaging Perspective

Han SB, Kim H, Skuba A, Tessler A, Ferguson T, Son YJ

Injured primary sensory axons fail to regenerate into the spinal cord, leading to chronic pain and permanent sensory loss. Re-entry is prevented at the dorsal root entry zone (DREZ), the...
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Medaka Fish Parkinson's Disease Model

Matsui H, Gavinio R, Takahashi

The teleost fish has been widely used in creating neurodegenerative models. Here we describe the teleost medaka fish Parkinson's disease (PD) models we developed using toxin treatment and genetic engineering....
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