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Capsaicin Blocks the Hyperpolarization-Activated Inward Currents via TRPV1 in the Rat Dorsal Root Ganglion Neurons

Kwak J

Capsaicin, the pungent ingredient in hot pepper, activates nociceptors to produce pain and inflammation. However, prolonged exposures of capsaicin will cause desensitization to nociceptive stimuli. Hyperpolarization-activated cation currents (Ih) contribute...
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Neurochemical Properties of Dental Primary Afferent Neurons

Vang H, Chung G, Kim HY, Park SB, Jung SJ, Kim JS, Oh SB

The long belief that dental primary afferent (DPA) neurons are entirely composed of nociceptive neurons has been challenged by several anatomical and functional investigations. In order to characterize non-nociceptivepopulation among...
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Differential Expressions of Synaptogenic Markers between Primary Cultured Cortical and Hippocampal Neurons

Kim YG, Lee YI

Primary dissociated neuronal cultures are widely used research tools to investigate of pathological mechanisms and to treat various central and peripheral nervous system problems including trauma and degenerative neuronal diseases....
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AMP-Activated Protein Kinase (AMPK) and Energy-Sensing in the Brain

Ramamurthy S, Ronnett G

5'-adenosine monophosphate-activated protein kinase (AMPK) is an evolutionarily conserved cellular and organismal energy integrator that responds to numerous stimuli with the overall intention to facilitate energy conservation and enhance energy...
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The Role of Protein Phosphorylation in the Gustatory Cortex and Amygdala During Taste Learning

Adaikkan C, Rosenblum

Protein phosphorylation and dephosphorylation form a major post-translation mechanism that enables a given cell to respond to ever-changing internal and external environments. Neurons, similarly to any other cells, use protein...
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