Skip Navigation
Skip to contents
Filter

ARTICLE TYPE

PUBLICATION DATE

7 results
Display

TFAP2C-mediated upregulation of TGFBR1 promotes lung tumorigenesis and epithelial–mesenchymal transition

Kim W, Kim E, Lee S, Kim D, Chun J, Park KH, Youn H, Youn B

TFAP2C (transcription factor-activating enhancer-binding protein 2C) expression has been positively correlated with poor prognosis in patients with certain types of cancer, but the mechanisms underlying TFAP2C-mediated tumorigenesis in non-small-cell lung...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Aldehyde dehydrogenase is used by cancer cells for energy metabolism

Kang JH, Lee SH, Hong D, Lee JS, Ahn HS, Ahn JH, Seong TW, Lee CH, Jang H, Hong KM, Lee C, Lee JH, Kim SY

We found that non-small-cell lung cancer (NSCLC) cells express high levels of multiple aldehyde dehydrogenase (ALDH) isoforms via an informatics analysis of metabolic enzymes in NSCLC and immunohistochemical staining of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A phosphorylation pattern-recognizing antibody specifically reacts to RNA polymerase II bound to exons

Han J, Lee JH, Park S, Yoon S, Yoon A, Hwang DB, Lee HK, Kim MS, Lee Y, Yang WJ, Youn HD, Kim H, Chung J

The C-terminal domain of RNA polymerase II is an unusual series of repeated residues appended to the C-terminus of the largest subunit and serves as a flexible binding scaffold for...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner

Oh IS, Textoris-Taube K, Sung PS, Kang W, Gorny X, Kähne T, Hong SH, Choi YJ, Cammann C, Naumann M, Kim JH, Park SH, Yoo OJ, Kloetzel P, Seifert U, Shin EC

By changing the relative abundance of generated antigenic peptides through alterations in the proteolytic activity, interferon (IFN)-γ-induced immunoproteasomes influence the outcome of CD8⁺ cytotoxic T lymphocyte responses. In the present...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
ROS homeostasis and metabolism: a critical liaison for cancer therapy

Kim J, Kim J, Bae JS

Evidence indicates that hypoxia and oxidative stress can control metabolic reprogramming of cancer cells and other cells in tumor microenvironments and that the reprogrammed metabolic pathways in cancer tissue can...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Integrated computational approach to the analysis of RNA-seq data reveals new transcriptional regulators of psoriasis

Zolotarenko A, Chekalin E, Mesentsev , Kiseleva L, Gribanova , Mehta R, Baranova A, Tatarinova TV, Piruzian E, Bruskin S

Psoriasis is a common inflammatory skin disease with complex etiology and chronic progression. To provide novel insights into the regulatory molecular mechanisms of the disease, we performed RNA sequencing analysis...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis

Jeong EM, Son YH, Choi Y, Kim JH, Lee JH, Cho SY, Kim IG

Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme that catalyzes crosslinking, polyamination or deamidation of glutamine residues in proteins. It has been reported that TG2 is involved in the pathogenesis...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr