- miR-27 regulates mitochondrial networks by directly targeting the mitochondrial fission factor
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Tak H, Kim J, Jayabalan , Lee H, Kang H, Cho DH, Ohn T, Nam SW, Kim W, Lee EK
- KMID: 2155388
- Exp Mol Med.
- 2014 Nov;46(11):e123.
- doi: 10.1038/emm.2014.73
Mitochondrial morphology is dynamically regulated by forming small, fragmented units or interconnected networks, and this is a pivotal process that is used to maintain mitochondrial homeostasis. Although dysregulation of mitochondrial... -
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- B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1
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Choi YW, Kim HJ, Kim YH, Park SH, Chwae YJ, Lee J, Soh EY, Kim JH, Park TJ
- KMID: 2155385
- Exp Mol Med.
- 2014 Nov;46(11):e120.
- doi: 10.1038/emm.2014.68
B-RafV600E mutant is found in 40-70% of papillary thyroid carcinoma (PTC) and has an important role in the pathogenesis of PTC. The sodium iodide symporter (NIS) is an integral plasma... -
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- Heme-binding-mediated negative regulation of the tryptophan metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1) by IDO2
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Lee YK, Lee HB, Shin DM, Kang MJ, Yi EC, Noh S, Lee J, Lee C, Min CK, Choi EY
- KMID: 2155386
- Exp Mol Med.
- 2014 Nov;46(11):e121.
- doi: 10.1038/emm.2014.69
Indoleamine 2,3-dioxygenases (IDOs) are tryptophan-catabolizing enzymes with immunomodulatory functions. However, the biological role of IDO2 and its relationship with IDO1 are unknown. To assess the relationship between IDO2 and IDO1,... -
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- (Lymph)angiogenic influences on hematopoietic cells in acute myeloid leukemia
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Lee JY, Kim HJ
- KMID: 2155387
- Exp Mol Med.
- 2014 Nov;46(11):e122.
- doi: 10.1038/emm.2014.72
The purpose of this review is to provide an overview of the effect of (lymph)angiogenic cytokines on hematopoietic cells involved in acute myeloid leukemia (AML). Like angiogenesis, lymphangiogenesis occurs in... -
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