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Ribosomal protein mutations in Korean patients with Diamond-Blackfan anemia

Chae H, Park J, Lee S, Kim M, Kim Y, Lee JW, Chung NG, Cho B, Jeong DC, Kim J, Kim JR, Park G

Diamond-Blackfan anemia (DBA) is a congenital bone marrow failure syndrome characterized by hypoproliferative anemia, associated physical malformations and a predisposition to cancer. DBA has been associated with mutations and deletions...
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Anti-inflammatory activity of compounds isolated from Astragalus sinicus L. in cytokine-induced keratinocytes and skin

Kim BH, Oh I, Kim JH, Jeon JE, Jeon B, Shin J, Kim TY

Inflammation is a part of the complex biological responses of a tissue to injury that protect the organ by removing injurious stimuli and initiating the healing process, and is considered...
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Recent progress in mucosal immunology and vaccine development

Kweon MN

No abstract available.
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Antigen targeting to M cells for enhancing the efficacy of mucosal vaccines

Kim SH, Jang YS

Vaccination is one of the most successful applications of immunology and for a long time has depended on parenteral administration protocols. However, recent studies have pointed to the promise of...
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Mucosal dendritic cells shape mucosal immunity

Chang SY, Ko HJ, Kweon MN

Dendritic cells (DCs) are key modulators that shape the immune system. In mucosal tissues, DCs act as surveillance systems to sense infection and also function as professional antigen-presenting cells that...
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New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development

Kurashima , Kiyono H

To achieve immune homeostasis in such a harsh environment as the intestinal mucosa, both active and quiescent immunity operate simultaneously. Disruption of gut immune homeostasis leads to the development of...
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Regulatory T-cell vaccination independent of auto-antigen

Pascual DW, Yang X, Holderness K, Jun S, Maddaloni , Kochetkova I

To date, efforts to treat autoimmune diseases have primarily focused on the disease symptoms rather than on the cause of the disease. In large part, this is attributed to not...
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Presence of multiple peripheral circadian oscillators in the tissues controlling voiding function in mice

Noh JY, Han DH, Kim MH, Ko IG, Kim SE, Park N, Choe HK, Kim KH, Kim K, Kim CJ, Cho S

Circadian clocks are the endogenous oscillators that harmonize a variety of physiological processes within the body. Although many urinary functions exhibit clear daily or circadian variation in diurnal humans and...
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