- Role of the epithelial-mesenchymal transition and its effects on embryonic stem cells
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Kim YS, Yi BR, Kim NH, Choi KC
- KMID: 2155373
- Exp Mol Med.
- 2014 Aug;46(8):e108.
- doi: 10.1038/emm.2014.44
The epithelial-mesenchymal transition (EMT) is important for embryonic development and the formation of various tissues or organs. However, EMT dysfunction in normal cells leads to diseases, such as cancer or... -
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- Diet control to achieve euglycemia induces significant loss of heart and liver weight via increased autophagy compared with ad libitum diet in diabetic rats
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Lee JH, Lee JH, Jin M, Han SD, Chon GR, Kim IH, Kim S, Kim SY, Choi SB, Noh YH
- KMID: 2155376
- Exp Mol Med.
- 2014 Aug;46(8):e111.
- doi: 10.1038/emm.2014.52
Intensive glucose control increases the all-cause mortality in type 2 diabetes mellitus (T2DM); however, the underlying mechanisms remain unclear. We hypothesized that strict diet control to achieve euglycemia in diabetes... -
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- Therapeutic effect of hepatocyte growth factor-secreting mesenchymal stem cells in a rat model of liver fibrosis
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Kim MD, Kim SS, Cha HY, Jang SH, Chang DY, Kim W, Suh-Kim H, Lee JH
- KMID: 2155375
- Exp Mol Med.
- 2014 Aug;46(8):e110.
- doi: 10.1038/emm.2014.49
Bone marrow-derived mesenchymal stromal cells (MSCs) have been reported to be beneficial for the treatment of liver fibrosis. Here, we investigated the use of genetically engineered MSCs that overexpress hepatocyte... -
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- SPA0355 attenuates ischemia/reperfusion-induced liver injury in mice
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Bae UJ, Yang JD, Ka SO, Koo JH, Woo SJ, Lee YR, Yu HC, Cho BH, Zhao HY, Ryu JH, Lee SM, Jeon R, Park BH
- KMID: 2155374
- Exp Mol Med.
- 2014 Aug;46(8):e109.
- doi: 10.1038/emm.2014.48
Hepatic ischemia/reperfusion (I/R) injury leads to oxidative stress and acute inflammatory responses that cause liver damage and have a considerable impact on the postoperative outcome. Much research has been performed... -
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