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AMP-activated protein kinase as a key molecular link between metabolism and clockwork

Lee Y, Kim EK

  • KMID: 2154252
  • Exp Mol Med.
  • 2013 Jul;45(7):e33.
Circadian clocks regulate behavioral, physiological and biochemical processes in a day/night cycle. Circadian oscillators have an essential role in the coordination of physiological processes with the cyclic changes in the...
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Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes

Kim NH, Hong BK, Choi SY, Moo Kwon H, Cho CS, Yi EC, Kim WU

  • KMID: 2154251
  • Exp Mol Med.
  • 2013 Jul;45(7):e32.
The activation of nuclear factor of activated T cells 5 (NFAT5), a well-known osmoprotective factor, can be induced by isotonic stimuli, such as activated Toll-like receptors (TLRs). It is unclear,...
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A known expressed sequence tag, BM742401, is a potent lincRNA inhibiting cancer metastasis

Park SM, Park SJ, Kim HJ, Kwon OH, Kang TW, Sohn HA, Kim SK, Moo Noh S, Song KS, Jang SJ, Sung Kim Y, Kim SY

  • KMID: 2154250
  • Exp Mol Med.
  • 2013 Jul;45(7):e31.
Long intergenic non-coding RNAs (lincRNAs) have historically been ignored in cancer biology. However, thousands of lincRNAs have been identified in mammals using recently developed genomic tools, including microarray and high-throughput...
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Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats

Oh TJ, Shin JY, Kang GH, Park KS, Cho YM

  • KMID: 2154249
  • Exp Mol Med.
  • 2013 Jul;45(7):e30.
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-alpha-dependent manner. We investigated whether a PPARalpha...
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