- Induction of steroid sulfatase expression by tumor necrosis factor-alpha through phosphatidylinositol 3-kinase/Akt signaling pathway in PC-3 human prostate cancer cells
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Suh BY, Jung JJ, Park N, Seong CH, Im HJ, Kwon Y, Kim D, Chun YJ
- KMID: 1025168
- Exp Mol Med.
- 2011 Nov;43(11):646-652.
- doi: 10.3858/emm.2011.43.11.073
Steroid sulfatase (STS) is responsible for the hydrolysis of aryl and alkyl steroid sulfates and has a pivotal role in regulating the formation of biologically active estrogens. STS may be... -
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- Higher infiltration by Th17 cells compared with regulatory T cells is associated with severe acute T-cell-mediated graft rejection
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Chung BH, Oh HJ, Piao SG, Sun IO, Kang SH, Choi SR, Park HS, Choi BS, Choi YJ, Park CW, Kim YS, Cho ML, Yang CW
- KMID: 1025166
- Exp Mol Med.
- 2011 Nov;43(11):630-637.
- doi: 10.3858/emm.2011.43.11.071
The aim of this study was to evaluate whether the Th17 and Treg cell infiltration into allograft tissue is associated with the severity of allograft dysfunction and tissue injury in... -
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- Enhanced skin wound healing by a sustained release of growth factors contained in platelet-rich plasma
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Yang HS, Shin J, Bhang SH, Shin JY, Park J, Im GI, Kim CS, Kim BS
- KMID: 1025165
- Exp Mol Med.
- 2011 Nov;43(11):622-629.
- doi: 10.3858/emm.2011.43.11.070
Platelet-rich plasma (PRP) contains growth factors that promote tissue regeneration. Previously, we showed that heparin-conjugated fibrin (HCF) exerts the sustained release of growth factors with affinity for heparin. Here, we... -
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- Lentivirus-mediated RNA interference targeting E2F-1 inhibits human gastric cancer MGC-803 cell growth in vivo
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Wang XT, Xie YB, Xiao Q
- KMID: 1025167
- Exp Mol Med.
- 2011 Nov;43(11):638-645.
- doi: 10.3858/emm.2011.43.11.072
The E2F-1 transcription factor is post-translationally modified and stabilized in response to various forms of DNA damage to regulate the expression of cell-cycle and pro-apoptotic genes. The sustained overexpression of... -
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- Simvastatin inhibits osteoclast differentiation by scavenging reactive oxygen species
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Moon HJ, Kim SE, Yun YP, Hwang YS, Bang JB, Park JH, Kwon IK
- KMID: 1025163
- Exp Mol Med.
- 2011 Nov;43(11):605-612.
- doi: 10.3858/emm.2011.43.11.067
Osteoclasts, together with osteoblasts, control the amount of bone tissue and regulate bone remodeling. Osteoclast differentiation is an important factor related to the pathogenesis of bone-loss related diseases. Reactive oxygen... -
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- Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis
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Hu HJ, Jin EH, Yim SH, Yang SY, Jung SH, Shin SH, Kim WU, Shim SC, Kim TG, Chung YJ
- KMID: 1025164
- Exp Mol Med.
- 2011 Nov;43(11):613-621.
- doi: 10.3858/emm.2011.43.11.068
Although the genetic component in the etiology of rheumatoid arthritis (RA) has been consistently suggested, many novel genetic loci remain to uncover. To identify RA risk loci, we performed a... -
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