- Evodiamine Reduces Caffeine-Induced Sleep Disturbances and Excitation in Mice
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Ko YH, Shim KY, Lee SY, Jang CG
- KMID: 2421720
- Biomol Ther.
- 2018 Sep;26(5):432-438.
- doi: 10.4062/biomolther.2017.146
Worldwide, caffeine is among the most commonly used stimulatory substances. Unfortunately, significant caffeine consumption is associated with several adverse effects, ranging from sleep disturbances (including insomnia) to cardiovascular problems. This... -
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- Pharmacokinetics, Pharmacodynamics and Safety of JES9501 after Single and Multiple Oral Administration in Healthy Subjects
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Kim A, Kim BH, Shin D, Cho JY, Yu KS, Jang IJ, Chung JY
- KMID: 2203227
- J Korean Soc Clin Pharmacol Ther.
- 2013 Dec;21(2):141-149.
- doi: 10.12793/jkscpt.2013.21.2.141
BACKGROUND: JES9501 is dehydroevodiamine, the extract of Evodia rutaecarpa, expected to be a new therapeutic for Alzheimer disease. This study aims to investigate the pharmacokinetics (PK), pharmacodynamics (PD) and safety... -
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- Euodia sutchuenensis Dode extract stimulates osteoblast differentiation via Wnt/beta-catenin pathway activation
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Hwang JH, Cha PH, Han G, Bach TT, Min DS, Choi KY
- KMID: 2155417
- Exp Mol Med.
- 2015 Mar;47(3):e152.
- doi: 10.1038/emm.2014.115
The Wnt/beta-catenin pathway has a role in osteoblast differentiation and bone formation. We screened 100 plant extracts and identified an extract from Euodia sutchuenensis Dode (ESD) leaf and young branch... -
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