- Single Nucleotide Deletion Mutation of KCNH2 Gene is Responsible for LQT Syndrome in a 3-Generation Korean Family
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Park JK, Oh YS, Choi JH, Yoon SK
- KMID: 1793058
- J Korean Med Sci.
- 2013 Sep;28(9):1388-1393.
- doi: 10.3346/jkms.2013.28.9.1388
Long QT syndrome (LQTS) is characterized by the prolongation of the QT interval in ECG and manifests predisposition to life threatening arrhythmia which often leads to sudden cardiac death. We... -
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- Inhibition of the Human Ether-a-go-go-related Gene (HERG) K+ Channels by Lindera erythrocarpa
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Hong HK, Yoon WJ, Kim YH, Yoo ES, Jo SH
- KMID: 1783138
- J Korean Med Sci.
- 2009 Dec;24(6):1089-1098.
- doi: 10.3346/jkms.2009.24.6.1089
Lindera erythrocarpa Makino (Lauraceae) is used as a traditional medicine for analgesic, antidote, and antibacterial purposes and shows anti-tumor activity. We studied the effects of Lindera erythrocarpa on the human... -
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- Genetic Mutation in Korean Patients of Sudden Cardiac Arrest as a Surrogating Marker of Idiopathic Ventricular Arrhythmia
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Son MK, Ki CS, Park SJ, Huh J, Kim JS, On YK
- KMID: 1777497
- J Korean Med Sci.
- 2013 Jul;28(7):1021-1026.
- doi: 10.3346/jkms.2013.28.7.1021
Mutation or common intronic variants in cardiac ion channel genes have been suggested to be associated with sudden cardiac death caused by idiopathic ventricular tachyarrhythmia. This study aimed to find... -
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- In vivo targeting of ERGpotassiumchannels inmice and dogs by a positron-emitting analogue of fluoroclofilium
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Kim SW, Yang SD, Ahn BJ, Park JH, Lee DS, Gessner G, Heinemann , Herdering , Yu KH
- KMID: 1093461
- Exp Mol Med.
- 2005 Aug;37(4):269-275.
The antiarrhythmic clofilium is an efficient blocker of hERG1 potassium channels that are strongly expressed in the heart. Therefore, derivatives of clofilium that emit positrons might be useful tools for... -
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