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Maturation of Erythroblasts in Human Liver during Ontogeny - An Electron Microscopic Study

Kim GY, Eom HY, Yang HC, Lee WB

  • KMID: 1529440
  • Korean J Anat.
  • 1997 Feb;30(1):15-28.
The hepatic hemopoiesis in intrauterine lifeis predominently erythropoiesis,and the erythroblasts undergo the differentiation process finally to form reticulocytes.In this syudy, the development of erythropoiesis in human fetal liver was observed...
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The Maturation of Circulating Primitive Erythroblasts in Human Embryos. A Karyometrical Study

Joo YS, Lee WB, Kim DC

The primitive erythroblasts in 21 cases of embryonic hearts from 4 to 9 weeks of gestation were studied with a light microscope. The nuclear diameter, the motosis, and the loss...
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Migration of Emperipoletic Erythroblasts Within Kupffer Cells in Human Hepatic Hemopoiesis: Electron Microscopic Study

Lee WB, Yoo DH, Chae HS, Bach JH, Kim SS, Kim KY

  • KMID: 1559109
  • Korean J Anat.
  • 2001 Jun;34(3):231-244.
The presence of erythroblasts within Kupffer cell was studied for transmission electron microscopically with 5 human fetal livers from 11 to 23 weeks of gestation during the high activity of...
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Exogenous c-Myc Blocks Differentiation and Improves Expansion of Human Erythroblasts In vitro

Geiler C, Andrade I, Greenwald

BACKGROUND: Engineered blood has the greatest potential to combat a predicted future shortfall in the blood supply for transfusion treatment. The production of red blood cells from hematopoietic stem cells...
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Genetically Engineered In Vitro Erythropoiesis

Geiler C, Andrade I, Clayton A, Greenwald

BACKGROUND: Engineered blood has the greatest potential to combat a predicted future shortfall in the US blood supply for transfusion treatments. Engineered blood produced from hematopoietic stem cell (HSC) derived...
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The Expression of Bcl-2 and Bax in Rat Hepatic Erythropoiesis

Chae HS, Bach JH, Yoo SJ, Kim DJ, Kim SS, Kim KY, Lee WB

  • KMID: 2030750
  • Korean J Anat.
  • 2002 Apr;35(2):143-152.
Hepatic erythropoiesis is a characteristic event of the fetal liver. Generally, the erythropoiesis shows 4 phases: developing (embryonic day (ED) 10 to 14), maximum flat (ED 14 to 16), decreasing...
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A Case of Extramedullary Hematopoiesis Associated with Congenital Dyserythropoietic Anemia

Han WH, Oh C, Han JW, Youn JK, Kim HY, Jung SE

It has been known that extramedullary hematopoiesis occurring after birth can be developed in various diseases, and it is often found in hematologic diseases. Among these, congenital dyserythropoietic anemia is...
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Relation of p53 Protein Overexpression to Subtypes of Acute Erythroleukemia

Park TH, Park TS, Oh SH, Kim HH, Lee EY, Chung JS, Kim MY, Lee JN, Kim KH, Han JY

  • KMID: 2089679
  • Korean J Clin Pathol.
  • 2001 Dec;21(6):451-458.
BACKGROUND: Acute erythroleukemia (AEL), FAB-M6 is a rare heterogenous disorder diagnosed by myeloblasts more than 30% of nonerythroid cells (NEC). Pure erythroleukemia (Di Guglielmo disease) with an excess of proerythroblasts...
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A Case of Transient Aplastic Crisis Induced by Human Parvovirus Bl9 in Hereditary Spherocytosis

Shin KS, Son BR, Lee DH

  • KMID: 2146194
  • Korean J Clin Pathol.
  • 1997 Dec;17(6):928-933.
Human parvovirus B19 is a single-strand DNA virus which causes erythema infectlosum, arthralgia, aplastic crisis in patients with red cell defect, chronic anemia in immunocompromised patients, and fetal hydrops in...
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Comparison of Serum-Free Media in RBC Differentiation from Human Hematopoietic Stem Cells

Kim JY, Kim S, Jeon YL, Choi Y, Kim HO

BACKGROUND: Research on RBC production from hematopoietic stem cells has been conducted competitively in many countries. However those were in vitro successes and many hurdles still remain for large scale...
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Expression of TGF-beta isoforms in the Human Fetal Hepatic Erythropoiesis

Kee SW, Kim YW, Kim SS, Kim KY, Lee WB

  • KMID: 2071840
  • Korean J Phys Anthropol.
  • 1999 Jun;12(1):23-32.
The expression patterns of transforming growth factor-betas (TGF-betas) were studied immunohis-tochemically in hepatic erythropoietic cells and hepatocytes of 3 human fetal livers from 21 to 26 gestation weeks. The results...
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Development of Sinusoidal Wall in Human Fetal Liver: A Morphological Study on Endothelial Cells, Kupffer Cells and Transmural Migration of Erythropoietic Cells

Lee WG, Kim KY, Lee WB

The 5 cases of human fetal liver aged from 11 to 23 weeks of gestation were investigated for the ultrastructure of sinusoidal wall by electron microscopy. The endothelial cells deficient...
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A Case of Pure Red Cell Aplasia Associated with B-cell Chronic Lymphocytic Leukemia

Lee JL, Kang HJ, Oh HA, Lee G, Lee KH, Hyun MS, Ryoo HM

  • KMID: 2252437
  • Korean J Hematol.
  • 2002 Feb;37(1):60-64.
Pure red cell aplasia (PRCA) is a rare disorder, which is characterized by severe anemia associated with reticulocytopenia and absence of erythroid precursor cells in the bone marrow. Recently we...
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Hydrops Fetalis Due to Parvovirus B19 Infection: Report of Two Autopsy Cases

Lee HC, Lee HE, Hwang PG, Chi JG, Park SH

  • KMID: 2277674
  • Korean J Pathol.
  • 2006 Jun;40(3):245-249.
Hydrops fetalis (HF) is a disease characterized by generalized subcutaneous edema and cavity effusion in the fetal stage. We report here on two autopsy cases of HF that were caused...
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Pure Red Cell Aplasia Caused by Acute Hepatitis A

Lee TH, Oh SJ, Hong S, Lee KB, Park H, Woo HY

Pure red cell aplasia is characterized as a normocytic anemia associated with reticulocytopenia and the absence of erythroblasts in the bone marrow. Pure red cell aplasia can be induced by...
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Evaluation of the ABX Pentra DX 120 for the Detection of Immature Cells in Peripheral Blood

Lee YK, Kang HJ, Kim YM, Won CY, Cho HC

  • KMID: 2040475
  • J Lab Med Qual Assur.
  • 2008 Dec;30(2):249-258.
INTRODUCTION: The ABX Pentra DX 120 (Pentra DX 120, ABX Diagnostics, Montpellier, France) adopted new technologies to perform differential leukocyte and erythroblast counts. The double matrix can discriminate Large Immature...
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Two Cases of Erythroleukemic Blast Crisis in Chronic Myelogenous Leukemia

Kim JY, Kim MS, Lim JH, Han KJ

  • KMID: 2089661
  • Korean J Clin Pathol.
  • 2001 Apr;21(2):93-97.
The erythroleukemic blast crisis in chronic myelogenous leukemia (CML) is rarely reported. We present two cases of erythroleukemic blast crisis of CML. In both cases, they had been treated with...
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A Case of Congenital Dyserythropoietic Anemia, Type II

Yang WK, Yoo JW, Cho HG, Park DC, Lee IS, Lee WY

  • KMID: 2142492
  • J Korean Pediatr Soc.
  • 1994 Jan;37(1):99-103.
Congenital dyserythropoietic anemia Type II (herditary erythroblatic multinuclearity with positive acidified serum test; HEMPAS) is characterized by binuclearity, multinuclearity, pluripolar mitoses, karyorrhexis of normoblasts, and the presence of abnormal antigens...
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Transmission and Scanning Electron Microscopic Studies on the Sinusoid and the Migration of Erythroid Cell in Rat Fetal Liver

Kim YW, Kim KY, Lee WB, Lee HS

  • KMID: 1530064
  • Korean J Anat.
  • 1998 Apr;31(2):281-292.
For studies on the developmental stages of migrating erythroid cells and the development of sinusoid, transmission and scanning electron microscopic observations were undertaken on rat fetal liver in 13, 15,...
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Development and Migration of Megakaryocyte during Hepatic Hemopoiesis in Human Fetuses

Lee WB, Lee CW, Chung BS, Kim BS, Kim DJ, Kim SS, Kim KY

  • KMID: 1559311
  • Korean J Anat.
  • 2002 Aug;35(4):285-296.
Liver tissuses obtained from 5 human fetuses between 11 weeks and 23 weeks of gestation during the high activity of hepatic hemopoiesis were observed with transmission electron microscope using continuous...
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