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Oxysterol (3,5-cholestadien-7-one, 5beta-cholestan-3-one, 5,24-cholestadien-3beta-OL) Induced Cytotoxicity and Apoptosis in Gallbladder Epithelial Cells

Choi HS, Kim YW

  • KMID: 772705
  • Korean J Gastroenterol.
  • 2004 Dec;44(6):328-336.
BACKGROUND/AIMS: Biliary epithelial cells are exposed to highly concentrated oxysterols. Therefore, oxysterols may play a role in pathogenesis of biliary tract diseases. We investigated the cytotoxic effect and apoptosis...
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Effects of Scutellarin on MUC5AC Mucin Production Induced by Human Neutrophil Elastase or Interleukin 13 on Airway Epithelial Cells

Jiang DP, Perelman J, Kolosov VP, Zhou XD

Scutellarin is a flavonoid extracted from a traditional Chinese herb, Erigeron breviscapus. The present study investigated the effect of scutellarin on MUC5AC mucin production and the possible mechanism. Human bronchial...
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Effects of Excretory/Secretory Products from Clonorchis sinensis and the Carcinogen Dimethylnitrosamine on the Proliferation and Cell Cycle Modulation of Human Epithelial HEK293T Cells

Kim EM, Kim JS, Choi MH, Hong ST, Bae YM

Clonorchis sinensis is one of the most prevalent parasitic helminths in Korea. Although cholangiocarcinoma can be induced by C. sinensis infection, the underlying mechanism is not clearly understood. To assess...
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Angiotensin III increases monocyte chemoattractant protein-1 expression in cultured human proximal tubular epithelial cells

Kim HW, Kim YO, Yoon SA, Han JS, Chun HB, Kim YS

BACKGROUND/AIMS: We investigated whether angiotensin III (Ang III) is involved in monocyte recruitment through regulation of the chemokine monocyte chemoattractant protein-1 (MCP-1) in cultured human proximal tubular epithelial cells (HK-2...
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Immunosuppression of xenograft rejection in porcine kidney PK15 cells by porcine IL-18

Choi YS, Kim YK, Shim JH, Kim EM, Kang HS, Yoon DY, Muneta Y, Myung PK

  • KMID: 1098092
  • Exp Mol Med.
  • 2006 Oct;38(5):574-582.
Xenotransplantation, the transplantation of cells, tissues or organs between individuals of different species, would resolve the current shortage of organs, but rejection remains the major hurdle to successful xenotransplantation. In...
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