- PSME4 determines mesenchymal stem cell fate towards cardiac commitment through YAP1 degradation
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Kim M, Kim YS, Ahn Y, Eom GH, Yoon S
- KMID: 2544142
- Korean J Physiol Pharmacol.
- 2023 Jul;27(4):407-416.
- doi: 10.4196/kjpp.2023.27.4.407
The regeneration of myocardium following acute circulatory events remains a challenge, despite numerous efforts. Mesenchymal stem cells (MSCs) present a promising cell therapy option, but their differentiation into cardiomyocytes is... -
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- Chimeric Antigen Receptor T Cell Therapy: A Novel Modality for Immune Modulation
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Yoon S, Eom GH
- KMID: 2468140
- Chonnam Med J.
- 2020 Jan;56(1):6-11.
- doi: 10.4068/cmj.2020.56.1.6
Cancer remains a leading cause of death, despite multimodal treatment approaches. Even in patients with a healthy immune response, cancer cells can escape the immune system during tumorigenesis. Cancer cells... -
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- HDAC and HDAC Inhibitor: From Cancer to Cardiovascular Diseases
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Yoon S, Eom GH
- KMID: 2152651
- Chonnam Med J.
- 2016 Jan;52(1):1-11.
- doi: 10.4068/cmj.2016.52.1.1
Histone deacetylases (HDACs) are epigenetic regulators that regulate the histone tail, chromatin conformation, protein-DNA interaction, and even transcription. HDACs are also post-transcriptional modifiers that regulate the protein acetylation implicated in... -
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- Serum Ferritin as a Diagnostic Biomarker for Kawasaki Disease
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Kim SH, Song ES, Yoon S, Eom GH, Kang G, Cho YK
- KMID: 2512690
- Ann Lab Med.
- 2021 May;41(3):318-322.
- doi: 10.3343/alm.2021.41.3.318
Diagnosis of Kawasaki disease (KD) is occasionally delayed because it is solely based on clinical symptoms. Previous studies have attempted to identify diagnostic biomarkers for KD. Recently, patients with KD... -
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- Sumoylation of histone deacetylase 1 regulates MyoD signaling during myogenesis
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Joung H, Kwon S, Kim KH, Lee YG, Shin S, Kwon DH, Lee YU, Kook T, Choe N, Kim JC, Kim YK, Eom GH, Kook H
- KMID: 2438357
- Exp Mol Med.
- 2018 Jan;50(1):e427.
- doi: 10.1038/emm.2017.236
Sumoylation, the conjugation of a small ubiquitin-like modifier (SUMO) protein to a target, has diverse cellular effects. However, the functional roles of the SUMO modification during myogenesis have not been... -
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- Clinical Characteristics of Autosomal Dominant Giant Platelet Syndromes and Mutation Analysis of MYH9
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Kook H, Nam HS, Baek HJ, Kim YO, Eom GH, Kee HJ, Cho D, Shin MG, Lee JJ, Kim HJ, Kook H, Hwang TJ
- KMID: 2252323
- Korean J Hematol.
- 2006 Mar;41(1):16-27.
- doi: 10.5045/kjh.2006.41.1.16
BACKGROUND: The autosomal dominant giant platelet syndromes (GPS), characterized by triads of giant platelets, thrombocytopenia, and Dohle-like leukocyte inclusions are caused by MYH9 mutation, a gene encoding the nonmuscle myosin... -
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