- Endothelin increases intracellular free calcium in isolated rat nephron
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Cha SH, Cho YJ, Lee KH, Endou H
- KMID: 1554767
- Korean J Physiol Pharmacol.
- 1997 Oct;1(5):565-572.
In the freshly isolated rat nephron, the effect of endothelin-1, -2 and -3 (ET-1, -2 and -3) on cytosolic free calcium concentration ((Ca2+)i) was determined using the fluorescent indicator Fura-2/AM. (Ca2+)i increase was... -
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- Oxidative Stress and Chronic Allograft Nephropathy
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Ha H, Park J, Kim YS, Endou H
- KMID: 1726167
- Yonsei Med J.
- 2004 Dec;45(6):1049-1052.
- doi: 10.3349/ymj.2004.45.6.1049
Oxidative stress defined as outbalanced generation of reactive oxygen species (ROS) than the existing antioxidative defense mechanisms plays an important role in tissue injury. Ischemia/reperfusion accompanied during organ transplantation is... -
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- Physiological, Pharmacological and Toxicological Implications of Heterodimeric Amino Acid Transporters
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Kanai Y, Endou H
- KMID: 2285295
- Korean J Physiol Pharmacol.
- 2004 Jun;8(3):117-128.
The heterodimeric amino acid transporter family is a subfamily of SLC7 solute transporter family which includes 14-transmembrane cationic amino acid transporters and 12-transmembrane heterodimeric amino acid transporters. The members of... -
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- JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells
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Choi DW, Kim DK, Kanai Y, Wempe MF, Endou H, Kim JK
- KMID: 2395254
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):599-607.
- doi: 10.4196/kjpp.2017.21.6.599
Most normal cells express L-type amino acid transporter 2 (LAT2). However, L-type amino acid transporter 1 (LAT1) is highly expressed in many tumor cells and presumed to support their increased... -
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