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Acting mechanisms of extracellular Ca2+ and Ca2+-antagonists on endothelium-derived relaxing factor in rabbit aorta

Jin SH, Suh KP, Suh SH, Kim KW

  • KMID: 1687174
  • Korean J Thorac Cardiovasc Surg.
  • 1991 Mar;24(3):229-244.
No abstract available.
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Mechanism of Action of Endothelium-Dependent Relaxation Substances on Rabbit Corpus Cavernosum

Kim JJ, Chung DY, Koh SK

  • KMID: 1851751
  • J Korean Androl Soc.
  • 1994 Dec;12(2):109-117.
Many relaxation substances cause endothelium-dependent vasodilation of various vessels. Relaxation of penile corpus cavernosum smooth muscle is controlled by nerves and a substance known as endothelium-derived relaxation factor(EDRF). The...
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Effects of Vanadate on the Contractility of Vascular Smooth Muscle

Song GH, Ahn DS, Chung HJ, Kang BS

Vanadate is a trace element in animal tissues and has been known to inhibit NA(+)-K(+) ATPase in various tissues including skeletal and cardiac muscles and smooth muscles. Vanadate shows contractile...
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Effect of Maturation on Endothelium-Dependent Relaxation in Pulmonary Arteries of the Newborn Rabbit

Seo BH, Lee SH, Park KI, Park MS, Lee C, Han DG

  • KMID: 2144571
  • J Korean Soc Neonatol.
  • 2001 Nov;8(2):247-256.
PURPOSE: This study was done to determine whether maturatin alters endothelium- dependent responses in pulmonary arteries. METHODS: Vascular rings of pulmonary arteries, with and without endothelium, taken from rabbits of...
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Experimental study of the role of nitric oxide of cavernous smooth muscle relaxation

Yoon JH, Jung GW, Cha YI

  • KMID: 1913160
  • Korean J Urol.
  • 1993 Jun;34(3):431-438.
Relaxation of penile cavernous smooth muscle is controlled by nerve and endothelium derived substances. Externally applied acetylcholine in human corpus cavernosum has been shown to cause endothelium dependent smooth muscle...
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The Effect of Saponin on the Vascular Contractility of the Rabbit Aortic Ring

Park KS, Kim MY, Lee HY, Choi EJ, Paik KS, Kang BS

PURPOSE: There have been conflicting reports on vascular response to Panax ginseng. The conflicting reports may be due to difference of ingredient of Panax ginseng. The aim of the present...
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The Effect of Hypoxia on the Release of Endothelium-derived Relaxing Factor in Rabbit Thoracic Aorta

Choi SS

  • KMID: 2062943
  • Korean J Thorac Cardiovasc Surg.
  • 2009 Oct;42(5):588-596.
BACKGROUND: To clarify the effect of hypoxia on vascular contractility, we tried to show whether hypoxia induced the release of endothelium-derived relaxing factor (EDRF) and the nature of the underlying...
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The iNOS Expression and Apoptosis in Psoriasis Vulgaris, Lichen Planus and Bowen's Disease

Choi YJ, Choi HY, Myung KB

  • KMID: 2303393
  • Korean J Dermatol.
  • 1999 Apr;37(4):449-458.
BACKGROUND: Nitric oxide(NO), a multifunctional mediator, is known as a endothelium-derived relaxing factor, a neurotransmitter, and a killer molecule formed by activated immune cells and participates in tissue destruction via...
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Endothelium-Dependent Vasodilation Responses in the Patients with Congestive Heart Failure

Zo JH, Kim CH

BACKGROUND: Many studies reported that endothelium-dependent vasodilator response is impaired in patients with congestive heart failure. But the opposite results also were reported. The aim of this study was to...
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Involvement of ATPase in Impaired Endothelium-Dependent Relaxation of Rabbit corpus Cavernosum Smooth Muscle Induced by Hypercholesterolemia

Kim IK, Ro BS, Han JY, Han KJ, Kim SC

  • KMID: 1960308
  • J Korean Androl Soc.
  • 1997 Jun;15(1):21-28.
PURPOSE: To investigate the involvement of ATPase in impaired relaxation of the cavernous smooth muscle by endothelium-dependent vasodilators in the hypercholesterolemic rabbit. METHODS: We measured th activity of total ATPase, Na,...
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Cavernosal Response to Nonadrenergic-Noncholinergic Stimulation Compared with Response to Exogenous Nitric Oxide

Jung GW, Yoon JH

  • KMID: 2058572
  • J Korean Androl Soc.
  • 1995 Jan;13(1):7-12.
Nitric oxide (NO) has been known to be endothelium-derived relaxing factor (EDRF) and the nonadrenergic-noncholinergic (NANC) neurotransmitter involved in the relaxation of cavernous smooth muscle. This study was initiated...
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The Role of Nitric Oxide in the Relaxation of Canine Corpus Cavernosum Smooth Muscle

Hong JH, Kim KS, Ahn TY

  • KMID: 2289722
  • Korean J Urol.
  • 1994 Aug;35(8):841-845.
Nitric Oxide(NO) has been known to be endothelium-derived relaxing factor in blood vessels, and to be nonadrenergic-noncholinergic(NANC) neurotransmitter involved in the relaxation of corpus cavernosum smooth muscle of man and...
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Effects of Propofol on Hypoxic Pulmonary Vasoconstriction after Pretreatment with L-NAME and Glibenclamide in Isolated Rat Lungs

Lee JH, Kim SD, Lee CH

BACKGROUND: It is generally accepted that propofol does not inhibit hypoxic pulmonary vasoconstriction (HPV). However, because the previous studies for the effects of propofol on HPV were established in...
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The Effect of Pentaspan on The Vascular Tone of The Isolated Rat Abdominal Aorta and Renal Artery

Suh JK, Kim JW, Jun JH, Shim JC, Kim KH, Lee DH, Kim KS, Yoo HK, Seung IS, Chon SU

The Pentaspan is a high molecular weight(250,000), hyperosmolar(320 mOsm/l) colloid solution and blood volume expander in clinical practice. Many researches revealed the decreasing of systemic vascular resistance and pulmonary vascular...
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Extracellular K+ Effects on the Mouse Aortic Endothelial Cell Contractility

Ahn JH, You JY

  • KMID: 2010951
  • Korean J Thorac Cardiovasc Surg.
  • 2003 Dec;36(12):887-893.
BACKGROUND: External stimuli increases intracellular (IC) Ca2+, which increases extracellular (EC) K+. To verify K+ effects on the vascular contraction, we performed an experiment using mouse aortic endothelial cell. MATERIAL...
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Prostacyclin synthase C1117A polymorphism is not associated with variant angina

Seong IW, Lim DS, Kim JH, Lee JH, Choi SW, Jeong JO

  • KMID: 1652684
  • Korean J Med.
  • 2004 Apr;66(4):383-388.
BACKGROUND: Coronary artery spasm plays an important role in the pathogenesis of variant angina (VA). Prostacyclin is one of the endothelium derived relaxing factors. The association between the novel single...
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Two Cases of Nitric Oxide Inhalation for Treatment of Severe Pulmonary Hypertension after Surgical Repair of Congenital Diaphragmatic Hernia

Chang YS, Kang IS, Park WS, Lee SK, Kim HH, Lee HJ

  • KMID: 2208179
  • J Korean Pediatr Soc.
  • 1996 Nov;39(11):1611-1619.
Nitric oxide, an endothelium-derived relaxing factor, is a selective pulmonary vasodilator. We have built and settled down the delivery system of nitirc oxide gas inhalation for the first time in...
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Effects of Endothelium-derived Relaxing Factors on the Regulation of ATP-sensitive Potassium Channel Activity in Cardiac Myocytes

Ju JM, Shin DH, Jeong HS, Park HW, Cho JG, Kim JH

BACKGROUND AND OBJECTIVES: Effects of the three major endothelium-derived relaxing factors (EDRFs), namely nitric oxide (NO), prostacyclin (PGI2), and 11, 12-epoxyeicosatrienoic acid (EET) on the ATP-sensitive potassium channel (K ATP...
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Effect of Teramethylammonium on the Release of Endothelium-Derived Relaxing Factor in Rabbit Thoracic Aorta

Lee YH, Ahn KS, Paik KS, Kang BS

Teramethylammonium(TMA) in one of the synthetic compounds of nicotine that act at ganglionic site. The major action of TMA consists of initial stimulation followed by a more persistent depression of...
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The action of Halothane and Isoflurane in Aortic Rings of Rabbit Pretreated with LNAME (L-nitrow arginine methyl ester) and MB (methylene blue)

Kwon EJ, Lim SH

BACKGROUND: The action of the volatile anesthetics on various organs in the body is not well known. Since Furchgott (1980) discovered endothelium derived relaxing factor (EDRF) from endothelium, many studies...
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