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Activities of different cysteine proteases of Paragonimus westermani in cleaving human IgG

Chung YB, Yang HJ, Kang SY, Kong Y, Cho SY

Cleaving host immunoglobulins is a well known mechanism of evading host immune reactions exploited by helminth parasites. Secreted cysteine proteases of helminth are a part of enzymes cleaving host IgG....
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Partial characterization of a 17 kDa protein of Clonorchis sinensis

Chung YB, Chung BS, Choi MH, Chai JY, Hong ST

A 17 kDa protein from Clonorchis sinensis adults was purified by a procedure including Sephacryl S-200 HR gel filtration and Q-Sepharose anion exchange chromatography. The protein was proved to be...
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Asp 280 residue is important in the activity of the Escherichia coli leader peptidase

Sung MS, Park KS

  • KMID: 1029933
  • Exp Mol Med.
  • 1999 Jun;31(2):64-69.
Leader peptidase is a novel serine protease in Escherichia coli, which catalyzes the cleavage of amino-terminal signal sequences from exported proteins. It is an integral membrane protein containing two transmembrane segments with...
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Differential expression of the 27 kDa cathepsin L-like cysteine protease in developmental stages of Spirometra erinacei

Kong Y, Yun DH, Cho SY, Sohn WM, Chung YB, Kang SY

The 27 kDa cathepsin L-like cysteine protease of Spirometra erinacei plerocercoid is known to play an important function in tissue penetration, nutrient uptake and immune modulation in human sparganosis. In...
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Partial Purification and Characterization of a Cysteine Protease Inhibitor from the Plerocercoid of Spirometra erinacei

Chung YB, Yang HJ

Helminthic cysteine proteases are well known to play critical roles in tissue invasion, nutrient uptake, and immune evasion of the parasites. In the same manner, the sparganum, the plerocercoid of...
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Intactness of zona pellucida does not affect the secretion of a trypsin-like protease from mouse blastocyst

Hwang SS, Lee EY, Chung YC, Yoon BK, Lee JH, Choi DS

Assisted hatching (AH), which is known to improve the hatching potential of mammalian embryos, has been used to increase the pregnancy rate in in vitro fertilization cycles. However, the effect...
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Degranulation of human eosinophils induced by Paragonimus westermani-secreted protease

Shin MH, Chung YB, Kita H

Eosinophil degranulation is considered to be a key effector function for the killing of helminthic worms and tissue inflammation at worm-infected lesion sites. However, relatively little data are available with...
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Epstein-Barr Virus-Associated Peripheral T-Cell Lymphoma involving Spleen in a Renal Transplant Patient

Lee HK, Kim HJ, Lee EH, Kim SY, Park TI, Kang CS, Yang WI

The incidence of posttransplantation lymphoproliferative disorders (PTLDs) has increased in recent years. Although rare, various types of T-cell lymphoma have been reported and their association with Epstein-Barr virus (EBV) has...
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Biological and biochemical modulation of Trichomonas vaginalis KT9 isolate after shifting of culture medium from TPS-1 into TYM

Ryu JS, Choi R, Park SY, Park H, Min DY

To evaluate the biological and biochemical characteristics of Trichomonas vaginalis KT9 isolate, the growth and size of trichomonads, pathogenicity in mouse, protein profiles and proteinase activity were examined after...
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Protease and Protease-Activated Receptor-2 Signaling in the Pathogenesis of Atopic Dermatitis

Lee SE, Jeong SK, Lee SH

Proteases in the skin are essential to epidermal permeability barrier homeostasis. In addition to their direct proteolytic effects, certain proteases signal to cells by activating protease-activated receptors (PARs), the G-protein-coupled...
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Granzyme B immunoreactivity in T/natural killer cell lymphomas

Cho MS, Lee MK, Yang WI, Yoon JH

Granzyme B is one of the serine proteases expressed in natural killer (NK) cells and activated cytotoxic T-lymphocytes. To evaluate the usefulness of granzyme B immunoreactivity in the diagnosis of...
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