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Study of UV DNA Repair Endonucleases with Respect to Skin Cancers

Kim J, Nam YS, Park YI

  • KMID: 2059124
  • J Korean Cancer Assoc.
  • 1997 Aug;29(4):599-607.
No abstract available
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A study of the [Ca2+] and the apoptosis of the KB cell lines after 10 Gy irradiation

Moon JW, Lee SS, Heo MS, Park TW, You DS

  • KMID: 1999518
  • J Korean Acad Oral Maxillofac Radiol.
  • 1999 Feb;29(1):105-117.
PURPOSE: Ionizing radiations have been reported as an apoptosis initiating stimulus in various cells and it has established that sustained elevations in [Ca2+] can lead to DNA fragmentation by Ca2+-dependent...
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Genetic Polymorphism of Cytochrome P450 2E1 in Hepatocellular Carcinoma Patients in Korea

Paik SW, Yoon JH, Hwang YJ, Jang YH, Lee HS, Kim CY

  • KMID: 2084763
  • Korean J Gastroenterol.
  • 1997 Oct;30(4):503-512.
Background/Airns: Cytochrome P450 2E1 (CYP2EI) is the only enzyme that rnetabolizes very low doses of N-nitrosodimethylamine (NDMA) and is characterized by its ethanol inducibility. Recently, it has been shown in...
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A Study of Epidermal Apoptosis

Park YL, Whang KU, Park JH

  • KMID: 2086019
  • Korean J Dermatol.
  • 1998 Feb;36(1):59-70.
BACKGROUND: Apoptosis is a highly selective form of cell suicide with characteristic morphologieal and biochemical features, including chromatin condensation, formation of apoptotic bodies, and DNA fragmentation by the activation of...
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ERCC1 Predicts a Poorer Platinum-based Chemotherapy Outcome but a Better Outcome for Uracil-Tegafur in the Resected Stage I-II NSCLC

Ryu HS, Xu X, Kim H, Lee JS, Jheon S, Chung JH

  • KMID: 2277519
  • Korean J Pathol.
  • 2011 Feb;45(1):45-52.
BACKGROUND: The role of excision repair cross-complementation group 1 (ERCC1) has been controversial in non-small cell lung cancer (NSCLC) patients who received adjuvant chemotherapy with a platinum agent. We investigated...
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The Expression of ERCC1, RRM1, and BRCA1 in Breast Cancer According to the Immunohistochemical Phenotypes

Kim D, Jung W, Koo JS

We studied the expression of BRCA1, ERCC1, and RRM1 which play an important role in DNA repair systems in breast cancer. Immunohistochemical staining for EGFR, BRCA1, ERCC1, and RRM1 were...
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Human FEN-1 can process the 5'-flap DNA of CTG/CAG triplet repeat derived from human genetic diseases by length and sequence dependent manner

Lee SM, Park MS

  • KMID: 931883
  • Exp Mol Med.
  • 2002 Sep;34(4):313-317.
Trinucleotide repeat (TNR) instability can cause a variety of human genetic diseases including myotonic dystrophy and Huntington's disease. Recent genetic data show that instability of the CAG/CTG repeat DNA...
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Emerging antimicrobial resistance, plasmid profile and pulsed-field gel electrophoresis pattern of the endonuclease-digested genomic DNA of Neisseria gonorrhoeae

Lee K, Shin JW, Lim JB, Kim YA, Yong D, Oh HB, Chong Y

Resistant gonococci are very prevalent in many countries, particularly in Asia. This study was conducted to determine the trend of resistance, the effect of decreasing the ciprofloxacin susceptibilities of gonococci...
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PCR-based detection of genes encoding virulence determinants in Staphylococcus aureus from bovine subclinical mastitis cases

Kalorey DR, Shanmugam , Kurkure NV, Chousalkar KK, Barbuddhe

The present study was carried out to genotypically characterize Staphylococcus aureus (S. aureus) isolated from bovine mastitis cases. A total of 37 strains of S. aureus were isolated during processing...
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Association between excision repair cross-complementation group 1 polymorphism and clinical outcome of platinum-based chemotherapy in patients with epithelial ovarian cancer

Kang S, Ju W, Kim JW, Park NH, Song YS, Kim SC, Park SY, Kang SB, Lee HP

  • KMID: 1094158
  • Exp Mol Med.
  • 2006 Jun;38(3):320-324.
ERCC1 is a DNA repair gene and has been associated with resistance to DNA damaging agents. In this study we hypothesized that a polymorphism of ERCC1 Asn118Asn (C->T) might affect...
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