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Effect of Bicarbonate Supplementation on Renal Function and Nutritional Indices in Predialysis Advanced Chronic Kidney Disease

Jeong J, Kwon SK, Kim HY

Current practice guidelines recommend alkali therapy in patients with chronic kidney disease (CKD) and metabolic acidosis to prevent complications. This study aims to investigate the effect of oral sodium bicarbonate...
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Epidermal Proteinase-Activated Receptor-2 Expression is Increased in End-Stage Renal Disease Patients with Pruritus: A Pilot Study

Moon SJ, Kim HJ, Cho SB, Lee SH, Choi HY, Park HC, Ha SK

Uremic pruritus is a common problem in patients with end-stage renal disease (ESRD), but the underlying mechanisms are not yet fully understood. We aimed to investigate the association between severity...
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Effect of Dialysate Sodium Concentration on Sodium Gradient and Hemodialysis Parameters

Jin H, Lee SY, Lee SN, Song JH, Kim MJ, Lee SW

This retrospective study was performed to determine the ranges of the sodium gradient (SG) between the dialysate sodium concentration (DNa) and serum sodium concentration (SNa) in hemodialysis (HD) patients and...
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Cisplatin-induced Kidney Dysfunction and Perspectives on Improving Treatment Strategies

Oh GS, Kim HJ, Shen A, Lee SB, Khadka D, Pandit A, So HS

Cisplatin is one of the most widely used and highly effective drug for the treatment of various solid tumors; however, it has dose-dependent side effects on the kidney, cochlear, and...
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How do We Manage Coronary Artery Disease in Patients with CKD and ESRD?

Choi HY, Park HC, Ha SK

Chronic kidney disease (CKD) has been shown to be an independent risk factor for cardiovascular events. In addition, patients with pre-dialysis CKD appear to be more likely to die of...
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Gaps between Global Guidelines and Local Practices in CKD-MBD

Kim GH

The term 'chronic kidney disease-mineral bone disorder' (CKD-MBD) is a new term that, in contrast to the old term 'renal osteodystrophy', implies a systemic syndrome associated with cardiovascular morbidity and...
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