- Constitutive Expression of MAP Kinase Phosphatase-1 Confers Multi-drug Resistance in Human Glioblastoma Cells
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Yu H, Park J, Lee J, Choi K, Choi C
- KMID: 1972728
- Cancer Res Treat.
- 2012 Sep;44(3):195-201.
PURPOSE: Current treatment of glioblastoma after surgery consists of a combination of fractionated radiotherapy and temozolomide. However, it is difficult to completely remove glioblastoma because it has uncertain boundaries with... -
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- 12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity
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Lee JW, Ryu HC, Ng YC, Kim C, Wei JD, Sabaratnam V, Kim JH
- KMID: 1383800
- Exp Mol Med.
- 2012 Jun;44(6):378-386.
12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. Despite the high level of 12-HHT present in tissues and bodily fluids,... -
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- The mitogen-activated protein kinase phosphatase-1 (MKP-1) gene is a potential methylation biomarker for malignancy of breast cancer
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Chen FM, Chang HW, Yang SF, Huang YF, Nien PY, Yeh YT, Hou MF
- KMID: 1383797
- Exp Mol Med.
- 2012 May;44(5):356-362.
The mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1) belongs to the MAPK cascades which are central to cell proliferation and apoptosis. The carcinogenic role of MKP-1 has been reported in many... -
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