- Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3
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Sung HJ, Choi SM, Yoon YS, An KS
- KMID: 1029923
- Exp Mol Med.
- 1999 Dec;31(4):174-178.
Tanshinone II-A is a derivative of phenanthrene-quinone isolated from Salvia miltiorrhiza BUNGE, a traditional herbal medicine that is known to induce antiinflammatory, anti-oxidative and cytotoxic activity. We have... -
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- Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IkappaB/NF-kappaB, in atherosclerotic cell model
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Qiu L, Xu R, Wang S, Li S, Sheng H, Wu J, Qu Y
- KMID: 2155425
- Exp Mol Med.
- 2015 Jul;47(7):e171.
- doi: 10.1038/emm.2015.37
Pentraxin 3 (PTX3) was identified as a marker of the inflammatory response and overexpressed in various tissues and cells related to cardiovascular disease. Honokiol, an active component isolated from the... -
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- Cryptotanshinone but not tanshinone IIA inhibits angiogenesisin vitro
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Hur JM, Shim JS, Jung HJ, Kwon HJ
- KMID: 755752
- Exp Mol Med.
- 2005 Apr;37(2):133-137.
In the course of screening of angiogenesis inhibitor from natural products, cryptotanshinone from Salvia miltiorrhiza was isolated as a potent small molecule inhibitor of angiogenesis. Cryptotanshinone inhibits bFGF-induced angiogenesis of... -
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