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Clinical effects of doxazosin in the treatment of essential hypertension

Kim KS, Kim JH, Lim HK, Lee BH, Lee JK

  • KMID: 1691759
  • Korean J Crit Care Med.
  • 1993 Jun;8(1):21-26.
No abstract available.
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A Case of Gynecomastia Induced by Use of Doxazosin

Park IS, Yi NH, Park CH, Park SW, Yu JS, Jeong JH

Doxazosin is an adrenergic alpha-1 receptor antagonist used to treat lower urinary tract symptoms that are common in prostatic hyperplasia. To our knowledge, few cases of gynecomastia and mastodynia, as...
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Clinical Effects of Doxazosin in Essential Hypertension

Joo YD, Lee IH, Kim DS, Lee KS

The antihypertensive efficacy and safety of doxazosin, a selective alpha1-inhibitor, were assessed in 20 patients with essential hypertension. Doxazosin induced a clinically significant reduction in blood pressure(26.0mmHg in systolic blood...
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Effects of Doxazosin Mesylate in Patients with Benign Prostatic Hyperplasia

Chang DJ, Park PA, Byun CY, Yea SH, Cho SR

  • KMID: 2139407
  • Korean J Urol.
  • 1994 May;35(5):509-514.
The clinical effect of doxazosin mesylate, a selective long acting alpha-1 adrenergic blocker, were evaluated in 31 patients with symptomatic benign prostatic hyperplasia ranging from 49- 85 years old. All...
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Effects of Doxazosin on Sexual Function in Patients with Benign Prostatic Hyperplasia

Cho YH, Kim DG, Lee KS

  • KMID: 2293610
  • Korean J Urol.
  • 2004 Feb;45(2):130-134.
PURPOSE: The goal of this study is to estimate the effect of doxazosin GITS on sexual function of patients with benign prostatic hyperplasia using the validated international index of erectile...
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Reappraisal of Antihypertensive Medicine Doxazosin and Carvedilol as a Potential Therapeutic for Hepatic Fibrosis

Paik YH

No abstract available.
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An Economic Evaluation of Pharmacological Therapy and Transurethral Resection of the Prostate for the Treatment of Benign Prostatic Hyperplasia

Lee DJ, Cho JS, Chung BS

  • KMID: 2292644
  • Korean J Urol.
  • 2002 Jul;43(7):619-623.
PURPOSE: An economic analysis of pharmacological therapy and transurethral resection of the prostate (TURP) for patients with benign prostatic hyperplasia (BPH) was conducted. MATERIALS AND METHODS: Twenty six patients had undergone...
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The Effect of Finasteride, Tamsulosin and Doxazosin Therapy on Sexual Function in Patients with Benign Prostatic Hyperplasia

Choi WS, Moon KH

  • KMID: 2293506
  • Korean J Urol.
  • 2004 Aug;45(8):777-782.
Purpose: The aim of this study was to evaluate the effect on sexual function after finasteride, tamsulosin, doxazosin single or combination therapy according the sexual function state before these therapies....
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The Effectiveness and Safety of Doxazosin GITS in Hypertension when Added to non-Responders to Monotherapy

Shin HH

BACKGROUND AND OBJECTIVES: Doxazosin GITS (Gastrointestinal Therapeutic System) greatly minimizes the need for titration by changing the drug-delivery rate and pharmacokinetic profile. No data are available on the safety and...
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The Proper Patient Selection for the Effective Response of Doxazosin in the Management of Benign Prostatic Hyperploasia

Kim YD, Lee JG

  • KMID: 2292447
  • Korean J Urol.
  • 2001 Jan;42(1):65-68.
PURPOSE: Doxazosin has gained wide acceptance as a pharmacotherapeutic agents for the treatment of BPH. As a selective alpha-1 blocker, it is known to reduce symptom scores and improve flow...
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Comparison of Different Alpha-blocker Combinations in Male Hypertensives with Refractory Lower Urinary Tract Symptoms

Lee KC, Kim JG, Cho SY, Jeon JS, Cho IR

PURPOSE: We compared the efficacy and safety profiles of dose increase, traditional combination methods, and combining different alpha blockers in hypertensive males with lower urinary tract symptom (LUTS) refractory to...
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Silencing of Heat Shock Protein 27 Expression Accelerates Doxazosin-induced Apoptosis in Prostate Cancer Cell Line PC-3

Shin SC, Cho JM, Kang JY, Yoo TK, Cho H

PURPOSE: Heat shock proteins (HSPs) are highly expressed during stress responses and cellular adaptation to environmental changes. One such protein is HSP27, a 27kDa protein that prevents cell death induced...
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The Efficacy and Safety of Doxazosin GITS in Patients with Benign Prostatic Hyperplasia

Chung BH, Park EK, Hong SJ

  • KMID: 2293405
  • Korean J Urol.
  • 2004 Jul;45(7):667-673.
PURPOSE: The doxazosin-gastrointestinal therapeutic system (GITS) greatly minimizes the need for titration by changing the drug-delivery rate and pharmacokinetic profiles. This multi-center study was designed to evaluate the efficacy and...
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Clinical Experience of Symptomatic Management of BPH with Terazosin, Doxazosin or Combination of Terazosin and Finasteride

Jeong DH, Park YI

  • KMID: 2290156
  • Korean J Urol.
  • 1998 Aug;39(8):772-776.
PURPOSE: We evaluated and compared the efficacy of terazosin, doxazosin and terazosin(alpha-1 adrenoreceptor antagonist) with finasteride(5-alpha reductase inhibitor) in the treatment of patient with benign prostatic hyperplasia (BPH). MATERIALS AND...
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The Effect of Doxazosin Premedication on Urinary Retention after Epidural Morphine

Lim HK, Lee HS, Chung CK, Han JU, Park HJ, Song JH, Cha YD, Kim TJ

BACKGROUND: Urinary retention is the most common and distressing complication in the postoperative period after an epidural morphine administration. In this prospective placebo-controlled study, the efficacy of doxazosin on preventing...
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Drug Interaction Study of Vardenafil 20mg and Doxazosin 4mg or Tamsulosin 0.2mg in Patients with Benign Prostatic Hyperplasia and Erectile Dysfunction to Evaluate Changes in Blood Pressure

Lee SY, Kim SC, Kim HW

Purpose: This study aimed at evaluating the expected additive blood pressure (BP) lowering effect of vardenafil when administered in the background of chronic alpha1-blocker therapy. Materials and Methods: Patients (n=90) with...
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Clinical Trial with Tamsulosin and Doxazosin for the Treatment of Premature Ejaculation in Patients with Co-morbid LUTS: a Comparative Study

Hong YK, Park DS, Hong JY, Chung JS, Jeong SJ, Hong SK, Lee SE, Jang SH, Kim JI

  • KMID: 2298778
  • Korean J Androl.
  • 2009 Apr;27(1):49-54.
PURPOSE: We wanted to evaluate the therapeutic potential of a low dose of tamsulosin, as compared with doxazosin, for the treatment of premature ejaculation in men with lower urinary tract...
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Doxazosin in the Symptomatic Treatment of Benign Prostatic Hyperplasia

Chung BH, Chung HJ, Hong SJ, Lee MS, The Korean Doxazosin Study Group

  • KMID: 2290325
  • Korean J Urol.
  • 1999 May;40(5):607-612.
PURPOSE: This study set out to investigate the safety and efficacy of doxazosin treatment in symptomatic patients with benign prostatic hyperplasia(BPH) in Korea. MATERIALS AND METHODS: A total of 237 male...
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Comparison of relaxation responses of cavernous and trigonal smooth muscles from rabbits by alpha1-adrenoceptor antagonists; prazosin, terazosin, doxazosin, and tamsulosin

Seo KK, Lee MY, Lim SW, Kim SC

Alpha1a-adrenergic receptor (AR) primarily mediates the contraction of the prostatic and cavernous smooth muscles. Among clinically available alpha1-AR antagonists for the medical management of benign prostatic hyperplasia (BPH), tamsulosin has...
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Expression of Heat Shock Protein 27 in Prostate Cancer Cell Lines According to the Extent of Malignancy and Doxazosin Treatment

Lee SW, Lee JW, Chung JH, Jo JK

  • KMID: 2320822
  • World J Mens Health.
  • 2013 Dec;31(3):247-253.
PURPOSE: Heat shock protein 27 (HSP27) is known as the material that plays a role in apoptosis control in tumor and cell protection including the immune response, drug tolerance, and...
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