- Deletions of 9p21 and TP53 in bladder cancer
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Park WS, Oh MJ, Lee HK, Lee KO, Rhyu MG, Dong SM, Lee JY, Kim SH
- KMID: 644955
- J Korean Med Sci.
- 1996 Jun;11(3):233-238.
- doi: 10.3346/jkms.1996.11.3.233
The objective of this study was to characterize the alterations of 9p21 and TP53 in Korean transitional bladder cancer and to assess the relationship between the histopathologic parameter and the... -
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- YKP1447, A Novel Potential Atypical Antipsychotic Agent
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Dong SM, Kim YG, Heo J, Ji MK, Cho JW, Kwak BS
- KMID: 2071654
- Korean J Physiol Pharmacol.
- 2009 Apr;13(2):71-78.
- doi: 10.4196/kjpp.2009.13.2.71
(S)-Carbamic acid 2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-1-phenyl-ethyl ester hydrochloride (YKP1447) is a novel "atypical" antipsychotic drug which selectively binds to serotonin (5-HT2A, Ki=0.61 nM, 5-HT2C, Ki=20.7 nM) and dopamine (D2, Ki=45.9 nM, D3, Ki=42.1... -
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- Loss of Heterozygosity on Chromosome 9p21, 17p13 and 3p in Human Astrocytic Tumor
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Lee YS, Kang CS, Dong SM, Lee JY, Shim SI, Kim BK
- KMID: 1725821
- Korean J Pathol.
- 2001 Aug;35(4):330-337.
BACKGROUND: The purpose of this study was to determine the genetic abnormalities of chromosomes 9p21, 17p13.1, 3p25 and 3p14.2 in the development and progression of astrocytic tumors. METHODS: We performed... -
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- Loss of Heterozygosity at VHL, FHIT, and p16 Loci in Nonpapillary Renal Cell Carcinoma
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Park WS, Dong SM, Cho YH, Hwang TG, Kim SY, Shin MS, Pi JH, Lee SH, Yoo NJ, Lee JY
- KMID: 1725466
- Korean J Pathol.
- 1999 Jan;33(1):8-14.
The objectives of this study were to characterize the alterations of 3p and 9p in sporadic renal cell carcinomas (RCC) and to assess the relationship between the clinical stages or... -
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- Identification of Zinc Finger Genes that are Differentially Expressed upon Apoptosis of Ramos B Cells
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Shin MS, Kim SY, Dong SM, Na EY, Lee SH, Park WS, Lee JY, Yoo NJ
- KMID: 2275698
- Korean J Pathol.
- 1998 Dec;32(12):1043-1048.
Typical programmed cell death requires de novo macromolecular synthesis and shares common morphological changes referred to as apoptosis. To elucidate the molecular mechanism of apoptosis, we isolated 13 cDNA clones... -
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- Identification of Differentially Expressed Genes Using RNA Fingerprinting in Cell after DNA Damage
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Lee JY, Shin MS, Dong SM, Na EY, Kim SY, Lee SH, Park WS, Yoo NJ
- KMID: 1725385
- Korean J Pathol.
- 1998 May;32(5):321-327.
RNA fingerprinting using on arbitrary primed polymerase chain reaction (RAP-PCR) was carried out to identify differentially expressed genes in HL-60 cell after treatment of methylmethane sulfonate (MMS). Twenty differentially expressed... -
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- Effects of a New Antipsychotic Drug (YKP1447) on Impaired Prepulse Inhibition Induced by Apomorphine and Phencyclidine in Rats
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Yoon BS, Park EH, Park EH, Kwon JT, Hong SB, Dong SM, Kim YH, Heo J, Ji MK, Kim YG, Kwak BS, Choi JS, Kim HT
- KMID: 2287438
- Korean J Psychopharmacol.
- 2008 Jan;19(1):38-45.
OBJECTIVE: Schizophrenia, a devastating mental disorder, displays a wide range of cognitive impairments including attentional impairment. Prepulse inhibition (PPI), in which a startle response to a loud acoustic noise is... -
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- The Role of gadd and p53 Genes in Apoptosis and Cell Cycle Delay by Genotoxic Agents
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Lee JY, Lee JD, Dong SM, Na EY, Shin MS, Kim SY, Lee SH, Park WS, Yoo NJ
- KMID: 2037280
- Korean J Pathol.
- 1998 Apr;32(4):239-247.
The aim of this study was to investigate the relationships between the gadd genes expression and an apoptosis induction in two different growing cell types after treatments with cisplatin and... -
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