- Oral Administration of Glycine and Leucine Dipeptides Improves Skin Hydration and Elasticity in UVB-Irradiated Hairless Mice
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Park JI, Lee JE, Shin HJ, Song S, Lee WK, Hwang JS
- KMID: 2389385
- Biomol Ther.
- 2017 Sep;25(5):528-534.
- doi: 10.4062/biomolther.2017.089
Placenta is a special organ that contains many nutrients such as growth factors, minerals, and bioactive peptides. Dipeptides of glycine and leucine are major components of porcine placenta extracts (PPE)... -
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- Biological functions of histidine-dipeptides and metabolic syndrome
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Song BC, Joo NS, Aldini G, Yeum KJ
- KMID: 2313704
- Nutr Res Pract.
- 2014 Feb;8(1):3-10.
The rapid increase in the prevalence of metabolic syndrome, which is associated with a state of elevated systemic oxidative stress and inflammation, is expected to cause future increases in the... -
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- Dipeptides Inhibit Melanin Synthesis in Mel-Ab Cells through Down-Regulation of Tyrosinase
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Lee HE, Kim EH, Choi HR, Sohn UD, Yun HY, Baek KJ, Kwon NS, Park KC, Kim DS
- KMID: 2011164
- Korean J Physiol Pharmacol.
- 2012 Aug;16(4):287-291.
- doi: 10.4196/kjpp.2012.16.4.287
This study investigated the effects of proline-serine (PS) and valine-serine (VS) dipeptides on melanogenesis in Mel-Ab cells. Proline-serine and VS significantly inhibited melanin synthesis in a concentration-dependent manner, though neither... -
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- Comparison of DPP-4 Inhibitors
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Kim NH, Kim SG
- KMID: 2173918
- J Korean Diabetes.
- 2013 Sep;14(3):111-119.
- doi: 10.4093/jkd.2013.14.3.111
During past several years, a novel class of antihyperglycemic agents, dipeptidyl peptidase-4 (DPP-4) inhibitors, has become one of the most important options in the management of type 2 diabetes. These... -
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- Decreased Prolidase Activity in Patients with Posttraumatic Stress Disorder
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Demir S, Bulut M, Atli A, Kaplan I, Kaya MC, Bez Y, Özdemir P, Sır A
- KMID: 2344740
- Psychiatry Investig.
- 2016 Jul;13(4):420-426.
- doi: 10.4306/pi.2016.13.4.420
OBJECTIVE: Many neurochemical systems have been implicated in the development of Posttraumatic Stress Disorder (PTSD). The prolidase enzyme is a cytosolic exopeptidase that detaches proline or hydroxyproline from the carboxyl... -
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- Hyperammonemic hepatic encephalopathy management through L-ornithin-L-aspartate administration in dogs
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Ahn JO, Li Q, Lee YH, Han SM, Hwang CY, Youn HY, Chung JY
- KMID: 2413146
- J Vet Sci.
- 2016 Sep;17(3):431-433.
- doi: 10.4142/jvs.2016.17.3.431
Seventeen dogs were treated with L-ornithin-L-aspartate (LOLA; experimental group). Three dogs were treated with lactulose recognized therapy (control group). Following LOLA administration, 15 dogs experienced a significant decrease in ammonia... -
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- Hepatic encephalopathy
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Kim CW
- KMID: 2256159
- Korean J Med.
- 2008 Jul;75(1):27-36.
Hepatic encephalopathy, one of the major complications of cirrhosis, is a neuropsychiatric syndrome caused by accumulation of toxins in the central nervous system following dysfunction in liver detoxification. Various manifestations... -
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- Roles of Matrix Metalloproteinases on Intracellular Staphylococcus aureus Growth in Bronchial Epithelial Cell
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Min BR, Lee YM, Park JS, Choi WI, Kwon KY
- KMID: 1478137
- Tuberc Respir Dis.
- 2008 Jan;64(1):22-27.
- doi: 10.4046/trd.2008.64.1.22
BACKGROUND: Staphylococcus aureus frequently colonizes and infects hospitalized patients. Respiratory infections with Staphylococcus aureus are common in patients with compromised airway defenses. However the mechanisms of S. aureus invasion from... -
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- Effects of vitamin C and E supplementation on oxidative stress and liver toxicity in rats fed a low-fat ethanol diet
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Lee SJ, Kim SY, Min H
- KMID: 2391962
- Nutr Res Pract.
- 2013 Apr;7(2):109-114.
We compared the preventive capacity of high intakes of vitamin C (VC) and vitamin E (VE) on oxidative stress and liver toxicity in rats fed a low-fat ethanol diet. Thirty-two... -
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- Clinical Effectiveness of Restriction Fragment Mass Polymorphism Assay for Human Papillomavirus Genotyping
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Lee EH, Lee KB, Kim EO, Ji SI, Shin SK, Lee HS, Shim SY, Kim SO, Hong SP
- KMID: 2040481
- J Lab Med Qual Assur.
- 2008 Dec;30(2):291-299.
BACKGROUND: Human papillomavirus (HPV) infection is the main cause of cervical cancer and with the advent of genotype specific vaccines, there is increased need for accurate, broad-spectrum and high-throughput methods... -
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- Calpains are Involved in Entamoeba histolytica-Induced Death of HT-29 Colonic Epithelial Cells
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Jang YS, Song KJ, Kim JY, Lee YA, Kim KA, Lee SK, Shin MH
- KMID: 1090619
- Korean J Parasitol.
- 2011 Jun;49(2):177-180.
- doi: 10.3347/kjp.2011.49.2.177
Entamoeba histolytica is an enteric tissue-invading protozoan parasite that can cause amebic colitis and liver abscess in humans. E. histolytica has the capability to kill colon epithelial cells in vitro;... -
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- Cinnamyl alcohol attenuates vasoconstriction by activation of K+ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase
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Kang YH, Yang IJ, Morgan KG, Shin HM
- KMID: 1402319
- Exp Mol Med.
- 2012 Dec;44(12):749-755.
Cinnamyl alcohol (CAL) is known as an antipyretic, and a recent study showed its vasodilatory activity without explaining the mechanism. Here we demonstrate the vasodilatory effect and the mechanism of... -
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