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Activin A Stimulates Mouse APCs to Express BAFF via ALK4-Smad3 Pathway

Kim JH, Seo GY, Kim PH

BACKGROUND: B cell-activating factor belonging to the TNF family (BAFF) is primarily expressed by macrophages and dendritic cells, and stimulates B cell proliferation, differentiation, survival, and Ig production. In the...
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MRI Findings of Long-term Survivals after Kasai Portoenterostomy

Jung J, Jung E, Park WH, Choi SO

The purpose of this study is to analyse clinical impact of specific MRI findings in liver in patients of long-term survivors after Kasai portoenterostomy (KPE). Twenty-eight patients who were underwent...
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Beta3-Adrenoceptor Agonists: Possible Role in the Treatment of Overactive Bladder

Igawa Y, Aizawa N, Homma Y

  • KMID: 2314580
  • Korean J Urol.
  • 2010 Dec;51(12):811-818.
In the present review article, we present an overview of beta-adrenoceptor (beta-AR) subtype expression at the mRNA and receptor protein levels in the human detrusor, the in vitro and in...
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Transcriptome Analysis of the Effects of Gomisin A on the Recovery of Carbon Tetrachloride-Induced Damage in Rat Liver

Choi YM, Choi IS, Lee SM, Hwang DY, Choi YW, Park YH

Gomisin A possesses a hepatic function-facilitating property in liver-injured rats. Its preventive action on carbon tetrachloride-induced cholestasis is due to maintenance of the function of the bile acids-independent fraction. To...
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Major clinical research advances in gynecologic cancer in 2015

Suh DH, Kim M, Kim HJ, Lee KH, Kim JW

In 2015, fourteen topics were selected as major research advances in gynecologic oncology. For ovarian cancer, high-level evidence for annual screening with multimodal strategy which could reduce ovarian cancer deaths...
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Comparison on the Efficacy and Safety of Biphenyl Dimethyl Dicarboxylate and Ursodeoxycholic Acid in Patients with Abnormal Alanine Aminotransferase: Multicenter, Double-blinded, Randomized, Active-controlled Clinical Trial

Lee SH, Cheon GJ, Kim HS, Kim YD, Kim SG, Kim YS, Jeong SW, Jang JY, Kim BS

BACKGROUND/AIMS: Chronic hepatocellular damage is closely associated with hepatic fibrosis and fatal complication in most liver diseases. The aim of this study is to compare the efficacy and safety of...
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The effect of diphenyl-dimethyl-dicarboxylate on cyclosporine-A blood level in kidney transplants with chronic hepatitis

Kim YS, Kim DH, Kim DO, Lee BK, Kim KW, Park JN, Lee JC, Choi YS, Rim H

  • KMID: 1038867
  • Korean J Intern Med.
  • 1997 Jan;12(1):67-69.
An adequate blood level of cyclosporine-A (CsA) is essential to keep graft function in kidney transplants. Due to a narrow therapeutic index and highly variable pharmacokinetic properties associated with CsA,...
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Protective Effect of Sauchinone Against Regional Myocardial Ischemia/Reperfusion Injury: Inhibition of p38 MAPK and JNK Death Signaling Pathways

Kim SJ, Jeong CW, Bae HB, Kwak SH, Son JK, Seo CS, Lee HJ, Lee J, Yoo KY

Sauchinone has been known to have anti-inflammatory and antioxidant effects. We determined whether sauchinone is beneficial in regional myocardial ischemia/reperfusion (I/R) injury. Rats were subjected to 20 min occlusion of...
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