- Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model
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Moon MH, Jeong JK, Lee JH, Park YG, Lee YJ, Seol JW, Park SY
- KMID: 1506224
- Exp Mol Med.
- 2012 Oct;44(10):603-614.
Higher levels of body fat are associated with an increased risk for development numerous adverse health conditions. FTY720 is an immune modulator and a synthetic analogue of sphingosine 1-phosphate (S1P),... -
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- Neuronal maturation in the hippocampal dentate gyrus via chronic oral administration of Artemisa annua extract is independent of cyclooxygenase 2 signaling pathway in diet-induced obesity mouse model
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Baek HK, Kim PS, Song JA, Choi DH, Kim DE, Oh SI, Park SK, Kim SJ, Song KD, Hwang IK, Seo HS, Yi SS
- KMID: 2412564
- J Vet Sci.
- 2017 Jun;18(2):119-127.
- doi: 10.4142/jvs.2017.18.2.119
Recently, we reported that Artemisia annua (AA) has anti-adipogenic properties in vitro and in vivo. Reduction of adipogenesis by AA treatment may dampen systemic inflammation and protect neurons from cytokine-induced... -
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- Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice
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Kim JK, Lee KS, Lee DK, Lee SY, Chang HY, Choi J, Lee JI
- KMID: 2155392
- Exp Mol Med.
- 2014 Dec;46(12):e127.
- doi: 10.1038/emm.2014.90
Nonalcoholic steatohepatitis (NASH) can progress into liver cirrhosis; however, no definite treatment is available. Omega-3 polyunsaturated fatty acid (omega-3) has been reported to alleviate experimental NASH, although its beneficial effect... -
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- The enhanced expression of IL-17-secreting T cells during the early progression of atherosclerosis in ApoE-deficient mice fed on a western-type diet
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Jeon US, Choi JP, Kim YS, Ryu SH, Kim YK
- KMID: 2155655
- Exp Mol Med.
- 2015 May;47(5):e163.
- doi: 10.1038/emm.2015.19
Atherosclerosis is a chronic progressive inflammatory disorder and the leading cause of cardiovascular mortality. Here we assessed the dynamic changes of T-cell-derived cytokines, such as inteferon (IFN)-gamma, interleukin (IL)-17 and... -
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