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Role of nitric oxide in the pathogenesis of diabetic nephropathy in streptozotocin-induced diabetic rats

Choi KC, Lee SC, Kim SW, Kim NH, Lee JU, Kang YJ

  • KMID: 759082
  • Korean J Intern Med.
  • 1999 Jan;14(1):32-41.
OBJECTIVES: Several reports suggest that enhanced generation or actions of nitric oxide (NO) have been implicated in the pathogenesis of glomerular hyperfiltration and hyperperfusion that occurs in early...
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Gene expression profile comparison in the penile tissue of diabetes and cavernous nerve injury-induced erectile dysfunction rat model

Kam SC, Lee SH, Jeon JH, So I, Chae MR, Park JK, Lee SW

PURPOSE: To investigate the effects of cavernous nerve injury (CNI) on gene expression profiles in the cavernosal tissue of a CNI-induced erectile dysfunction (ED) model and to provide a basis...
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Chlorogenic Acid Decreases Retinal Vascular Hyperpermeability in Diabetic Rat Model

Shin JY, Sohn J, Park KH

To evaluate the effect of chlorogenic acid (CGA), a polyphenol abundant in coffee, on retinal vascular leakage in the rat model of diabetic retinopathy, Sprague-Dawley rats were divided into four...
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Optimizing in vivo gene transfer into mouse corpus cavernosum by use of surface electroporation

Song KM, Choi MJ, Kwon MH, Ghatak K, Park SH, Ryu DS, Ryu JK, Suh JK

PURPOSE: Electroporation is known to enhance the efficiency of gene transfer through a transient increase in cell membrane permeability. The aim of this study was to determine the optimal conditions...
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