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The protective effect of Amomum xanthoides extract against alloxan-induced diabetes through the suppression of NFkappaB activation

Park BH, Park JW

  • KMID: 1085741
  • Exp Mol Med.
  • 2001 Jun;33(2):64-68.
This study was undertaken to investigate the preventive mechanism of Amomum xanthoides extract against the development of alloxan-induced diabetics of mice. Pretreatment of mice with A. xanthoides extract via intraperitoneum...
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The efficacy of SPA0355 in protecting beta cells in isolated pancreatic islets and in a murine experimental model of type 1 diabetes

Bae UJ, Song MY, Jang HY, Gim HJ, Ryu JH, Lee SM, Jeon R, Park BH

  • KMID: 2154270
  • Exp Mol Med.
  • 2013 Nov;45(11):e51.
Cytokines activate several inflammatory signals that mediate beta-cell destruction. We recently determined that SPA0355 is a strong anti-inflammatory compound, thus reporting its efficacy in protecting beta cells from various insults....
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