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Protease and Protease-Activated Receptor-2 Signaling in the Pathogenesis of Atopic Dermatitis

Lee SE, Jeong SK, Lee SH

Proteases in the skin are essential to epidermal permeability barrier homeostasis. In addition to their direct proteolytic effects, certain proteases signal to cells by activating protease-activated receptors (PARs), the G-protein-coupled...
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