- Expression of Heat Shock Protein 70 Modulates the Chemoresponsiveness of Pancreatic Cancer
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Hyun JJ, Lee HS, Keum B, Seo YS, Jeen YT, Chun HJ, Um SH, Kim CD
- KMID: 1712336
- Gut Liver.
- 2013 Nov;7(6):739-746.
BACKGROUND/AIMS: Heat shock protein (HSP) 70 is constitutively overexpressed in pancreatic cancer cells (PCCs) and appears to confer protection against chemotherapeutics. We investigated whether modulating HSP 70 increases chemoresponsiveness to... -
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- Pseudolaric Acid B Inhibits Proliferation, Invasion and Epithelial-to-Mesenchymal Transition in Human Pancreatic Cancer Cell
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Li X, Zhao X, Song W, Tian Z, Yang L, Niu Q, Zhang Q, Xie M, Zhou B, Xu Y, Wu J, Zhang C
- KMID: 2418844
- Yonsei Med J.
- 2018 Jan;59(1):20-27.
- doi: 10.3349/ymj.2018.59.1.20
PURPOSE: This study was aimed to investigate the effect of pseudolaric acid B (PAB) on proliferation, invasion and epithelial-to-mesenchymal transition (EMT) in pancreatic cancer cells and to explore the possible... -
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- The Effect of HIF-1alpha siRNA on Growth and Chemosensitivity of Mia-paca Cell Line
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Yang L, Kang WK
- KMID: 1084504
- Yonsei Med J.
- 2008 Apr;49(2):295-300.
- doi: 10.3349/ymj.2008.49.2.295
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) primarily mediates the hypoxic response. HIF-1alpha induction by various stimuli contributes to cell proliferation and survival. To investigate the effect of HIF-1alpha, we used small interfering... -
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- MicroRNA Expression Pattern in Intraductal Papillary Mucinous Neoplasm
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Park YG, Lee KH, Lee JK, Lee KT, Choi DW, Choi SH, Heo JS, Jang KT, Lee EM, Kim JO, Min SY, Kim EJ
- KMID: 1718427
- Korean J Gastroenterol.
- 2011 Oct;58(4):190-200.
- doi: 10.4166/kjg.2011.58.4.190
BACKGROUND/AIMS: Intraductal papillary mucinous neoplasms (IPMN) are precursor lesions of fatal pancreatic cancer. Physiological function of microRNA is to regulate the stability and translation of mRNA. The aberrant microRNA expression... -
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