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Sequence analysis of canine LINE-1 elements and p53 gene in canine transmissible venereal tumor

Choi YK, Kim CJ

  • KMID: 1097345
  • J Vet Sci.
  • 2002 Dec;3(4):285-292.
LINEs (long interspersed nuclear elements or long interspersed repeated DNA elements) contains two open reading frames (ORFs), ORF1 and ORF2. We analysed the ORF2 located in the 5' region to...
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Expression and Mutational Analysis of c-kit in Ovarian Surface Epithelial Tumors

Kim DJ, Lee MH, Park TI, Bae HI

Coexpression of Kit ligand and c-kit has been reported in some gynecologic tumors. To determine whether imatinib mesylate is useful in ovarian epithelial tumors, we performed immunohistochemical and mutational analysis....
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Mutations of p53 Tumor Suppressor Gene in Spontaneous Canine Mammary Tumors

Lee CH, Kweon OK

  • KMID: 1097349
  • J Vet Sci.
  • 2002 Dec;3(4):321-325.
Mutation of the p53 tumor suppressor gene has been related in the pathogenesis of numerous human and canine cancers, including breast cancers and mammary tumors. We have investigated exons 5-8...
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Hypermethylation of p16(INK4a) in Korean Non-small Cell Lung Cancer Patients

Hong YS, Roh MS, Kim NY, Lee HJ, Kim HK, Lee KE, Kwak JY, Kim JY

Promoter hypermethylation of the p16(INK4a) gene was investigated in 81 sets of samples of tumor tissue and adjacent normal tissue from Korean patients with primary lung cancer, using the modified...
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