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Upregulation of Proinflammatory Cytokines in the Fetal Brain of the Gaucher Mouse

Hong YB, Kim EY, Jung SC

Gaucher disease is caused by a deficiency of glucocerebrosidase. Patients with Gaucher disease are divided into three major phenotypes: chronic nonneuronopathic, acute neuronopathic, and chronic neuronopathic, based on symptoms of...
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Genetic Polymorphisms of Alcohol-metabolizing Enzymes and Cytokines in Patients with Alcohol Induced Pancreatitis and Alcoholic Liver Cirrhosis

Kim MS, Lee DH, Kang HS, Park HS, Jung S, Lee JW, Kwon KS, Kim PS, Kim HG, Shin YW, Kim YS, Baek I, Lee MS

  • KMID: 772650
  • Korean J Gastroenterol.
  • 2004 Jun;43(6):355-363.
BACKGROUND/AIMS: Susceptibility to organ damage induced by alcohol may be related to inherited variations (polymorphisms) in alcohol-metabolizing enzymes, or polymorphisms affecting cytokines. The aim of this study was to...
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Genetic controls of Th17 cell differentiation and plasticity

Dong C

CD4+ T lymphocytes play a major role in regulation of adaptive immunity. Upon activation, naive T cells differentiate into different functional subsets. In addition to the classical Th1 and Th2...
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Time Course Study of Cytokine mRNA Expression in LPS-Stimulated Porcine Alveolar Macrophages

Choi IS, Shin NR, Shin SJ, Lee DY, Cho YW, Yoo HS

  • KMID: 1095367
  • J Vet Sci.
  • 2002 Jun;3(2):97-101.
The kinetics of cytokine mRNA expression was studied in porcine alveolar macrophages using an RT-PCR assay. The expression levels of IFN- gamma, IL-2, IL-4, IL-6, GM-CSF, IL-12 p35, and IL-12...
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Expression Patterns of Cytokines and Chemokines Genes in Human Hepatoma Cells

Shin EC, Choi YH, Kim JS, Kim SJ, Park JH

Various cytokines and chemokines play a role in carcinogenesis. However, no study has previously been undertaken to investigate comprehensively the expressions of cytokines and chemokines in hepatoma cells. In this...
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Mycobacterium vaccae induces a strong Th1 response that subsequently declines in C57BL/6 mice

Zhang L, Jiang Y, Cui Z, Yang W, Yue L, Ma Y, Shi S, Wang C, Wang C, Qian A

Mycobacterium (M.) vaccae is a fast-growing species of saprophytic bacteria that is widely distributed. To understand the host immune responses induced by M. vaccae isolated from bovine submaxillary lymph nodes,...
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Biologic Therapy for Brain Cancers - Based on Cellular and Immunobiology

Okada H

The overall goal of our research projects is to develop effective immunotherapeutic regimens, particularly combining vaccine and gene therapy/ cell therapy strategies. For the development of clinically effective immunotherapy for...
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