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Genetic Susceptibility of CYP1A1 and GSTM1 to the Risk for Korean Bladder Transitional Cell Carcinoma

Jeong TY, Lee JJ, Shin KY, Park HY, Lee TY, Woo YN

  • KMID: 2292428
  • Korean J Urol.
  • 2000 Jan;41(1):158-165.
No abstract available.
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Effect of Nifedipine on Induction of Cytochrome P-450 1A1 and 2B1 in Spontaneously Hypertensive Rate

Hong YS, Kim HL, Park HY, Pae YS, Park SS

Cytochrome P-450(CYP) enzymes are important in catalyzing the hiotransffrmation on manyendogeneous compounds and xenobiotics, including drugs and carcinogens. In the presentstudy, effect of nifedipine a voltage dependent calcium channel blocker...
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A Case of Kaposi' s Sarcoma

Chun SI, Nam IW, Koh CJ

  • KMID: 1679024
  • Korean J Dermatol.
  • 1984 Oct;22(5):570-573.
Kaposi's sarcorna is a tumor-like condition which characterized by a mixed proliferation of fibroblastic components and vascular structures. The authors report a case of nodular type of Kaposis sarcoma in...
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Constitutive expression and changes of cytochrome P450 isozymes mRNAs by vehicles (petrolatum, DMSO, ethanol) in rat skin using semi-quantitative RT-PCR

Lee AY, Lee KH, Ko DS, Chey WY

  • KMID: 1607080
  • Korean J Physiol Pharmacol.
  • 2001 Oct;5(5):407-412.
Many drugs are primarily metabolized by the cytochrome P450s (CYPs). Drug metabolites would be important allergens for adverse drug reactions such as drug eruptions. Skin tests with a suspected drug have conducted to...
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A Case of Familial Benign Chronic Pemphigus

Lee JS, Chung EJ, Park SY

  • KMID: 1679061
  • Korean J Dermatol.
  • 1984 Dec;22(6):639-642.
We present a case of familial benign chronic pemphigus in 50-year-old male patient who had had recurrent oozing, macerated and eroded skin lesions on the groin and scrotum for 20...
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Osteomyelitis Resulting from Chronic Septic Olecranon Bursitis: Report of Two Cases

Moon MS, Kim ST, Park BK

We reported the two cases of olecranon osteomyelitis secondary to the iatrogenic chronic relapsing septic olecranon bursitis. Infection was well eradicated by excision of the infected bursa and curettage of...
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Correlation between Genetic Polymorphism of CYP2D6 and CYP1A1 and Susceptibility of Renal Cell Carcinoma in Korean

Park KW, Jung SI, Jung GW, Kwon HY, Jeong JS, Chun JH, Yoon JH

  • KMID: 2007098
  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):801-809.
PURPOSE: Many of the enzymes handling environmental factors are polymorphic and may confer variable susceptibility to renal cell carcinoma (RCC). Among those, the author studied genetic polymorphisms of CYP2D6 (B...
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A Case of Epidermolytic Hyperkeratosis

Wang HY, Choi YJ, Sung HS

  • KMID: 1679349
  • Korean J Dermatol.
  • 1985 Aug;23(4):507-510.
Epidermolytic hyperkeratosis, previously called bullous congenital ichthyosiform erythroderma is a dominantly inherited disorcler and usually manifested by blisters at or shortly after birth. We report a case of epidermolytic hyperkeratosis...
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A Case of Superficial Basal Cell Epithelioma of the Labium Majus

Lee EK, Park CJ, Yi JY, Lee EJ

A 40-year-old woman presented with a pruritic erythematous eroded patch on the right labium majus which had been for 3 years. Histopathological findings were consistent with superficial basal cell epithelioma....
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Fibrous Dysplasia: A Report of a Case

Zeong MS, Zeong WG, Kim DE

Fibrous dysplasia of bone is a disorder in which one or more bone lesions are present, but in which extraskeletal abnormalities not infrequently form part of the total disease complex....
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The Association between Pneumoconiosis and Genetic Polymorphism of GSTM1, GSTT1, GSTP1, NAT2, CYP2E1 and CYP1A1

Oh CJ, Hwang MY, Lee KJ, Lee HR, Cho BM

  • KMID: 1607562
  • Korean J Occup Environ Med.
  • 2005 Jun;17(2):85-94.
OBJECTIVES: To investigate effects of genetic polymorphism of glutathione S-transferase M1 (GSTM1), glutathione S-transferase T1 (GSTT1), glutathione S-transferase P1 (GSTP1), N-acetyltransferase (NAT2), cytochrome P450 2E1 (CYP2E1) and cytochrome P450 1A1...
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Effects of Genetic Factor, Life Styles, and Diet on Urinary Hippuric Acid Excretion in Toluene Exposed Workers

Yim HW, Park CY, Roh YM, Lee KS, Lee JM, Lee WC, Lee SH, Chung CK

  • KMID: 2028119
  • Korean J Occup Environ Med.
  • 2000 Sep;12(3):405-420.
OBJECTIVES: The purpose was to investigate the distributions and the effects of genetic polymorphism of aldehyde dehydrogenase 2(ALDH2), cytochrome P450 1A1(CYP1A1), and cytochrome P450 2E1(CYP2E1) on the toluene metabolism. METHODS:...
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Association of the polymorphisms in CYP1A1 and CYP1A2 genes with preterm premature rupture of membranes

Park CH, Shin JC, Yang DE, Park IY, Ko HS, Kim YH, Ahn HY, Kim SJ, Kim SP

  • KMID: 2272461
  • Korean J Obstet Gynecol.
  • 2004 Dec;47(12):2319-2324.
OBJECTIVE: Preterm delivery (PTD) is the leading cause of perinatal mortality and morbidity. However, its etiology and pathogenesis remain unknown in most cases. Recently, some research put forth the hypothesis...
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Association Studies of the Relationship Between Endometriosis and Polymorphism of the Detoxification Enzymes GSTT1, GSTM1, and CYP1A1

Shim SS, Hur SE, Lee KS, Moon HS, Ahn JJ, Yu HK, Kim HR, Chung HW

  • KMID: 2271972
  • Korean J Obstet Gynecol.
  • 2003 Feb;46(2):403-409.
OBJECTIVE: Enzymes belonging to the Glutathione S transferase and cytochrome P450 families are involved in the two-stage detoxification process of a number of pro-carcinogens. We genotyped each 74 women with...
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Association between Genetic Polymorphisms of the Cytochrome P-4501A1 and Susceptibility to Pancreatic Cancer

Lee HC, Yoon YB, Kim CY

  • KMID: 2240690
  • Korean J Gastroenterol.
  • 1997 Apr;29(4):522-529.
Rackground/Aims: Cigarette smoking is the best-established risk factor for pancreatic cancer. Metabolic activation is a prerequisite for the carcinogenic effect of many carcinogens, and the CYP1A1 activates polycyclic aromatic hydrocarbons...
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A Case of Herpes Genitalis Associated with Childhood Sexual Abuse

Seo KI, Kim KH, Choi JH

We report a case of recurrent herpes genitalis in a 5-year-old girl which was considered to result from childhood sexual abuse. The skin lesion was an eroded erythematous macule with...
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Association between genetic polymorphisms of the cytochromes P-450 (1A1, 2D6, and 2E1) and the susceptibility to pancreatic cancer

Lee HC, Yoon YB, Kim CY

  • KMID: 1051581
  • Korean J Intern Med.
  • 1997 Jun;12(2):128-136.
OBJECTIVES: Metabolic activation is a prerequisite for the carcinogenic effect of many carcinogens, and considerable interindividual variation exists in the metabolic capacity to activate the carcinogens. The cytochromes P-450 (CYPs)...
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Analysis of CYP1A1 , GST-mu and GST-theta Polymorphisms for the Determination of Genetic Susceptibility to Korean Gastric Cancer

Lee OY, Lee CG, Kwon SJ, Choi HS, Yoon BC, Hahm JS, Lee MH, Kee CS, Park KN, Sun HS

  • KMID: 2084880
  • Korean J Gastroenterol.
  • 1999 Jan;33(1):27-37.
BACKGROUND/AIMS: Genetic susceptibility to chemical carcinogens is one of the most important hos factors in human cancers. The genetically determined differences in metabolism related to cytochrome P450 (CYP450) and glutathione...
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Genetic Susceptibilities of Cytochrome P4501A1 and Glutathione S-transferase M1 to the Risk for Korean Head and Neck Squamous Cell Carcinoma Patients

Shin CS, Ahn KS, Tae K, Lee HS, Kim HJ, Kong G

  • KMID: 2074355
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Feb;42(2):202-208.
BACKGROUND AND OBJECTIVES: Individual genetic susceptibilities to chemical carcinogens have been recognized as a major important host factors in human cancers. The cytochrome P450 family (CYPs) and glutathione-S-transferase (GST) have...
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A Case of Calyceal Diverticlum Treated by Partial Nephrectomy

Lee KP, Kim K, Kim CK

  • KMID: 1911220
  • Korean J Urol.
  • 1973 Mar;14(1):71-74.
Authors present here in a calyceal diverticulum complicated by chronic pyelonephritis, which was diagnosed on urinalysis, IVP, RGP and symptoms. Partial nephrectomy was done and confirmation was made by specimen...
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