- Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers
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Park SR
- KMID: 2150754
- Immune Netw.
- 2012 Dec;12(6):230-239.
- doi: 10.4110/in.2012.12.6.230
Activation-induced cytidine deaminase (AID) is an enzyme that is predominantly expressed in germinal center B cells and plays a pivotal role in immunoglobulin class switch recombination and somatic hypermutation for... -
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- Concomitant AID Expression and BCL7A Loss Associates With Accelerated Phase Progression and Imatinib Resistance in Chronic Myeloid Leukemia
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Yu N, Shin S, Choi JR, Kim Y, Lee KA
- KMID: 2373641
- Ann Lab Med.
- 2017 Mar;37(2):177-179.
- doi: 10.3343/alm.2017.37.2.177
No abstract available. -
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- Molecular Pathogenesis of Gastric Cancer
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Park WS
- KMID: 2188286
- J Korean Med Assoc.
- 2010 Apr;53(4):270-282.
- doi: 10.5124/jkma.2010.53.4.270
In this article, I will survey the major genetic susceptibility and somatic genetic alterations involved in gastric cancer and adenoma. These include germline and somatic genetic alterations in oncogenes, tumor... -
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- The Relationship between Clinical Drug Sensitivity and Expression of Drug Resistance Genes in Patients with Acute Myelogenous Leukemia
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Kim KW, Kim HJ, Park SY
- KMID: 1832115
- Korean J Hematol.
- 2001 May;36(2):115-122.
BACKGROUND: The occurrence of drug resistance (DR) is one of the obstacles in the successful chemotherapeutic treatment of cancer. Multidrug resistance-1 (MDR-1), multidrug resistance associated protein (MRP), topoisomerase IIalpha (Topo... -
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- Interleukin-17 Enhances Germinal Center Formation and Immunoglobulin G1 Production in Mice
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Lee J, Lee SY, Kang CM, Jhun JY, Kim JH, Cho ML, Park SH, Kim HY, Kwok SK
- KMID: 2394342
- J Rheum Dis.
- 2017 Oct;24(5):271-278.
- doi: 10.4078/jrd.2017.24.5.271
OBJECTIVE: Interleukin (IL)-17 is a pro-inflammatory cytokine that has pleiotropic effects on multiple target cells and thereby contributes to the development of immune-mediated inflammatory disorders. However, the role of IL-17... -
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