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Acute myopathy induced by colchicine in a cyclosporine-treated renal transplant recipient--a case report and review of the literature

Lee BI, Shin SJ, Yoon SN, Choi YJ, Yang CW, Bang BK

We report a case of colchicine-induced myopathy related to short-term, customary administration of colchicine. A 49-year-old male was admitted because of muscle weakness and myalgia that had developed 10...
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Hydrogen Peroxide Upregulates TNF-Related Apoptosis-Inducing Ligand (TRAIL) Expression in Human Astroglial Cells, and Augments Apoptosis of T Cells

Kwon D, Choi IH

The brain is particularly vulnerable to oxygen free radicals, and these radicals have been implicated in the pathology of several neurological disorders. In this study, the modulation of TNF-related apoptosis-inducing...
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Short-term Efficacy of Topical Immunosuppressive Agents on the Survival of Cultivated Allo-Conjunctival Equivalents

Shin YJ, Kim MK, Oh JY, Wee WR, Lee JH, Ko JH, Lee HJ, Lee JL, Min BM, Sohn YS

PURPOSE: To investigate the short-term efficacy of topical immunosuppressive agents on the survival of cultivated allo-conjunctival equivalents. METHODS: Twenty-five eyes of New Zealand white rabbits were included. Temporal...
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Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense

Shin EH, Kim TH, Hong SJ, Park JH, Guk SM, Chai JY

The effects of anti-allergic drugs on intestinal mastocytosis and the expulsion of Neodiplostomum seoulense were observed in Sprague-Dawley rats, after oral infection with 500 metacercariae. The drugs used were hydroxyzine...
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Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction

Chae YJ, Kim HS, Rhim HS, Kim BE, Jeong SW, Kim IK

  • KMID: 1457543
  • Exp Mol Med.
  • 2001 Dec;33(4):284-292.
3-Deazaadenosine (DZA), a cellular methylation blocker was reported to induce the caspase-3-like activities-dependent apoptosis in U-937 cells. In this study, we analyzed the activation pathway of the caspase cascade involved...
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Induction of fibronectin gene expression by inhibitors of protein phosphatase type 2B in normal and transformed fibroblasts

Rhew JH, Shin YA, Lee BH, Park RW, Kim IS

  • KMID: 1029934
  • Exp Mol Med.
  • 1999 Jun;31(2):71-75.
Two intracellular signal pathways mediated by cAMP and protein kinase C (PKC) were involved in the regulation of FN gene expression (Lee et al., Exp. Mol. Med. 30: 240, 1998). In this...
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Effects of cyclosporin A on sex hormone and estrogen receptor in male rat with special reference to cyclosporin A-induced osteoporosis

Shin WY, Li SZ, Chung SS, Lee HC, Huh KB, Lim SK

The mechanisms of high turnover bone loss induced by Cyclosporin A (CsA) are not clearly understood. Deficiencies in sex hormones result in high turnover osteoporosis, and not only androgen but...
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