- Light microscopic and electron microscopic features of cyclosporine nephrotoxicity in rats
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Kim JY, Suh KS
- KMID: 644901
- J Korean Med Sci.
- 1995 Oct;10(5):352-359.
- doi: 10.3346/jkms.1995.10.5.352
In order to clarify morphologic changes associated with cyclosporine (CS) nephrotoxicity, CS in ethyl alcohol at 25 mg/kg/day i.p. was administered to male Sprague-Dawley rats for periods of 1 to... -
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- -Melanocyte Stimulating Hormone (MSH) decreases cyclosporine A induced apoptosis in cultured human proximal tubular cells
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Jo SK, Lee SY, Han SY, Cha DR, Cho WY, Kim HK, Won NH
- KMID: 2157569
- J Korean Med Sci.
- 2001 Oct;16(5):603-609.
- doi: 10.3346/jkms.2001.16.5.603
The pathogenesis of chronic cyclosporine A (CsA) nephrotoxicity has not been elucidated, but apoptosis is thought to play an important role in CsA induced tubular atrophy. Recently Fas-Fas ligand system... -
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- Activation of Intrarenal Complement System in Mouse Model for Chronic Cyclosporine Nephrotoxicity
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Kim YO, Lim SW, Li C, Kang HJ, Ahn KO, Yang HJ, Ghee JY, Kim SH, Kim JY, Choi BS, Kim J, Yang CW
- KMID: 724109
- Yonsei Med J.
- 2007 Jun;48(3):517-525.
- doi: 10.3349/ymj.2007.48.3.517
PURPOSE: Local activation of the complement system plays a role in target organ damage. The aim of our study was to investigate the influence of cyclosporine (CsA)- induced renal injury... -
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- Comparison of Early and Late Conversion of Sirolimus in Experimental Model of Chronic Cyclosporine Nephropathy
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Kim JY, Ghee JY, Lim SW, Piao SG, Chung BH, Yoon HE, Hwang HS, Choi BS, Kim J, Yang CW
- KMID: 1120153
- J Korean Med Sci.
- 2012 Feb;27(2):160-169.
- doi: 10.3346/jkms.2012.27.2.160
Sirolimus (SRL) is a promising drug for replacing calcineurin inhibitors. We performed this study to determine the optimal time of conversion from cyclosporine (CsA) to SRL in an experimental model... -
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- Induction of PPAR Gamma mRNA and Protein Expression by Rosiglitazone in Chronic Cyclosporine Nephropathy in the Rat
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Ahn KO, Lim SW, Yang HJ, Li C, Sugawara A, Ito S, Choi BS, Kim YS, Kim J, Yang CW
- KMID: 1779536
- Yonsei Med J.
- 2007 Apr;48(2):308-316.
- doi: 10.3349/ymj.2007.48.2.308
PURPOSE: We recently reported that rosiglitazone (RGTZ), a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist, has a protective effect against cyclosporine (CsA)- induced renal injury. Here we report the effect of... -
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