- Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor
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Jang JW
- KMID: 1381460
- Korean J Hepatol.
- 2008 Sep;14(3):305-308.
- doi: 10.3350/kjhep.2008.14.3.305
No abstract available. -
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- Molecular Targets of Dietary Polyphenols with Anti-inflammatory Properties
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Yoon JH, Baek SJ
- KMID: 2158137
- Yonsei Med J.
- 2005 Oct;46(5):585-596.
- doi: 10.3349/ymj.2005.46.5.585
There is persuasive epidemiological and experimental evidence that dietary polyphenols have anti-inflammatory activity. Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) have long been used to combat inflammation. Recently, cyclooxygenase (COX)... -
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- Effects of hypoxia on pulmonary vascular contractility
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Lee YH, Seo JH, Kang BS
- KMID: 711556
- Yonsei Med J.
- 1998 Jun;39(3):261-267.
- doi: 10.3349/ymj.1998.39.3.261
Although hypoxic pulmonary vasoconstriction (HPV) has been recognized by many researchers, the precise mechanism remains unknown. As isolated pulmonary arteries will constrict in vitro in the response to hypoxia, the... -
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- Mechanisms of relaxation of coronary artery by hypoxia
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Lee YH, Kim JT, Kang BS
- KMID: 711555
- Yonsei Med J.
- 1998 Jun;39(3):252-260.
- doi: 10.3349/ymj.1998.39.3.252
This study was designed to clarify the dependency of hypoxic coronary vasodilation (HCD) on the endothelium and the role of the K+ channels on HCD in the rabbit coronary artery.... -
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- Heterogeneous nuclear ribonuclear protein C is increased in the celecoxib-induced growth inhibition of human oral squamous cell carcinoma
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Lee EJ, Kim SH, Kwark YE, Kim J
- KMID: 1094145
- Exp Mol Med.
- 2006 Jun;38(3):203-209.
Celecoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) that is a critical factor in carcinogenesis, but precise mechanism of its action remains to be elucidated. Here we evaluated the inhibitory... -
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- Dexamethasone differentiates NG108-15 cells through cyclooxygenase1 induction
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Kim HS, Song M, Kim E, Ryu SH, Suh PG
- KMID: 1094702
- Exp Mol Med.
- 2003 Jun;35(3):203-210.
Cyclooxygenase (COX) is a key enzyme in the conversion of arachidonic acid into prostanoids which participate in various cellular functions including apoptosis, mitogenesis, inflammation, immune modulation and differentiation. Moreover, the... -
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- Role of Prostaglandins in Colon Cancer
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Myung SJ, Kim IH
- KMID: 1767526
- Korean J Gastroenterol.
- 2008 May;51(5):274-279.
Colon cancer is one of the major leading causes of cancer-related deaths in the Western countries. In Korea, the incidence of colon cancer is increasing due to changes in environment... -
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- Effects of Celecoxib and Nordihydroguaiaretic Acid on Puromycin Aminonucleoside-Induced Nephrosis in the Rat
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Lee DW, Kwak IS, Lee SB, Song SH, Seong EY, Chung HC, Yang BY, Lee MY, Sol MY
- KMID: 1778160
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S183-S188.
- doi: 10.3346/jkms.2009.24.S1.S183
The selective cyclooxygenase-2 (COX-2) and 5-lipoxygenase (LOX) inhibitors might inhibit prostaglandin synthesis and reduce proteinuria. The present study was designed to investigate the anti-proteinuric effects of nordihydroguaiaretic acid (NDGA) as... -
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- Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells
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Lee E, Choi MK, Han IO, Lim SJ
- KMID: 1094159
- Exp Mol Med.
- 2006 Jun;38(3):325-331.
SC-560, a strucutral analogue of celecoxib, induces growth inhibition in a wide range of human cancer cells in a cyclooxygenase (COX)-independent manner. Since SC-560 suppresses the growth of cancer cells... -
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