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Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Expression in Thyroid Neoplasms and Their Clinicopathological Correlation

Kim KH, Kim SH, Kim SH, Back JH, Park MJ, Kim JM

To evaluate the expressions of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in thyroid neoplasms in a Korean population, we studied a total of 154 cases: papillary carcinoma of...
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Expression of Cyclooxygenase-2, p53 and Ki-67 in Gastric Cancer

Joo YE, Chung IJ, Park YK, Koh YS, Lee JH, Park CH, Lee WS, Kim HS, Choi SK, Rew JS, Park CS, Kim SJ

It has been reported that p53 mutation may contribute to upregulate cyclooxygenase (COX)-2 expression that is observed in malignant tissues. These molecules are involved in carcinogenesis by affecting tumor cell...
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ERK-1/-2 and p38 Kinase Oppositely Regulate 15-deoxy-delta(12,14)-prostaglandinJ2-Induced PPAR-gamma Activation That Mediates Dedifferentiation But Not Cyclooxygenase-2 Expression in Articular Chondrocytes

Yoon EK, Lee WK, Lee JH, Yu SM, Hwang SG, Kim SJ

Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a ligand-activated transcription factor and plays an important role in growth, differentiation, and inflammation in different tissues. In this study, we investigated the effects...
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Cyclo-oxygenase-2 and p53 Immunoreactivity in Superficial Early Colorectal Carcinoma

Kim YS, Lim SD, Lee JK, Kim SE, Ryu SH, Lee JW, Moon JS

  • KMID: 772954
  • Korean J Gastroenterol.
  • 2006 May;47(5):350-356.
BACKGROUND/AIMS: De novo colorectal carcinoma shows more aggressive behavior including submucosal invasiveness. Both p53 and cyclo-oxygenase-2 (COX-2) have been shown to be involved in colon carcinogenesis, progression from adenoma to...
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