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Transcription of class II MHC gene by interferon-gamma in FRTL-5 cells

Lee MS, Lee JO, Kang TW, Lee JH

The intracellular mechanism by which interferon-gamma induces the expression of class II major histocompatibility complex (MHC) antigen in nonlymphoid cells is not clear. The effect of recombinant rat interferon-gamma...
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Regulation of bcl-2 family in hydrogen peroxide-induced apoptosis in human leukemia HL-60 cells

Lee JE, Sohn JW, Lee JH, Lee KC, Son CS, Tockgo YC

  • KMID: 927133
  • Exp Mol Med.
  • 2000 Mar;32(1):42-46.
Numerous types of cells have been shown to undergo apoptosis when exposed to oxidant agent such as hydrogen peroxide. In order to understand the functional relationship between the anti- and...
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Vibrio vulnificus cytolysin induces hyperadhesiveness of pulmonary endothelial cells for neutrophils through endothelial P-selectin: a mechanism for pulmonary damage by Vibrio vulnificus cytolysin

Kim BS, Kim JS

  • KMID: 931882
  • Exp Mol Med.
  • 2002 Sep;34(4):308-312.
Vibrio vulnificus cytolysin forms transmembrane pores that are permeable to calcium ions in pulmonary endothelial cells, and has been suggested as an important virulence factor that sequestrate neutrophils primarily...
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Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells

Kim KM, Lee KH, Hong YS, Park HY

  • KMID: 755108
  • Exp Mol Med.
  • 2000 Dec;32(4):246-254.
Fas transduces apoptotic signals upon cross-linking with the Fas ligand (FasL), which is experimentally replaced by agonistic anti-Fas monoclonal antibodies (mAb). Of eight human malignant hematopoietic cell lines...
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Molecular Identification of Schizophyllum commune as a Cause of Allergic Fungal Sinusitis

Won EJ, Shin JH, Lim SC, Shin MG, Suh SP, Ryang DW

Schizophyllum commune, a basidiomycetous fungus, rarely causes disease in humans. We report a rare case of allergic fungal sinusitis caused by S. commune in a 14-yr-old girl. The patient presented...
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15-Deoxy-delta12,14-PGJ2inhibits IL-6-induced Stat3 phosphorylation in lymphocytes

Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, Um JW, Sohn J, Song GG, Ji JD

  • KMID: 1056229
  • Exp Mol Med.
  • 2005 Jun;37(3):179-185.
15-deoxy-delta12,14-PGJ2(15d-PGJ2) is a natural ligand that activates the peroxisome proliferators-activated receptor (PPAR) gamma, a member of nuclear receptor family implicated in regulation of lipid metabolism and adipocyte differentiation. Recent studies...
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Quantitative in Vivo Detection of Brain Cell Death after Hypoxia Ischemia Using the Lipid Peak at 1.3 ppm of Proton Magnetic Resonance Spectroscopy in Neonatal Rats

Ahn SY, Yoo HS, Lee JH, Sung DK, Jung YJ, Sung SI, Lim KH, Chang YS, Lee JH, Kim KS, Park WS

This study was performed to determine the accuracy of proton magnetic spectroscopy (1H-MRS) lipid peak as a noninvasive tool for quantitative in vivo detection of brain cell death. Seven day-old...
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CD36 signaling inhibits the translation of heat shock protein 70 induced by oxidized low density lipoprotein through activation of peroxisome proliferators-activated receptor gamma

Lee KJ, Ha ES, Kim MK, Lee SH, Suh JS, Lee SH, Park KH, Park JH, Kim DJ, Kang D, Kim BC, Jeoung D, Kim YK, Kim HD, Hahn JH

Oxidized LDL (OxLDL), a causal factor in atherosclerosis, induces the expression of heat shock proteins (Hsp) in a variety of cells. In this study, we investigated the role of CD36,...
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