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Antimalarial Activity of C-10 Substituted Triazolyl Artemisinin

Park GM, Park H, Oh S, Lee S

We synthesized C-10 substituted triazolyl artemisinins by the Huisgen cycloaddition reaction between dihydroartemisinins (2) and variously substituted 1, 2, 3-triazoles (8a-8h). The antimalarial activities of 32 novel artemisinin derivatives were...
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Click Chemistry-Based Injectable Hydrogels and Bioprinting Inks for Tissue Engineering Applications

Gopinathan J, Noh I

BACKGROUND: The tissue engineering and regenerative medicine approach require biomaterials which are biocompatible, easily reproducible in less time, biodegradable and should be able to generate complex three-dimensional (3D) structures to...
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The Synthesis of the Stable IVDU Derivative for Imaging HSV-1 TK Expression

Kim EJ, Choi TH, Ahn SH, Kim BS, Park H, Cheon GJ, Rhee HJ, An GI

  • KMID: 1841153
  • Nucl Med Mol Imaging.
  • 2009 Oct;43(5):478-486.
PURPOSE: 5-iododeoxyuridine analogues have been exclusively developed for the potential antiviral and antitumor therapeutic agents. In this study, we synthesized carbocyclic radioiododeoxyuridineanalogue (ddIVDU) and carbocyclic intermediate as efficient carbocyclic radiopharmaceuticals. MATERIALS...
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