- Expression of cyclins in ductal hyperplasia, atypical ductal hyperplasia and ductal carcinoma in situ of the breast
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Kim HJ, Jung WH, Kim DY, Lee HD
- KMID: 711757
- Yonsei Med J.
- 2000 Jun;41(3):345-353.
- doi: 10.3349/ymj.2000.41.3.345
Cyclin/cdc complexes are known to function in cell-cycle regulation. Cyclin D1/cdk4 and -6 complexes, which functions as a G1-S checkpoint and cyclin B1/cdc2 complexes, a G2-M checkpoint are essential for... -
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- Changes in expression of cell cycle regulators and their hepatic lobular distribution in partial hepatectomy-induced regenerating rat liver
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Jeong JS, Lee JH, Kim HI, Park JI
- KMID: 646039
- J Korean Med Sci.
- 1999 Dec;14(6):635-642.
- doi: 10.3346/jkms.1999.14.6.635
Partial hepatectomy (PH) endorses quiescent hepatocytes to reenter the cell cycle. The regenerating liver returns to its preresection weight after 7 days, following one or two cell division and maintains... -
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- Immortalization of human embryonic fibroblasts by overexpression of c-myc and simian virus 40 large T antigen
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Kim HS, Shin JY, Yun JY, Ahn DK, Lee JY
- KMID: 1457544
- Exp Mol Med.
- 2001 Dec;33(4):293-298.
SV40 large T antigen, a viral oncoprotein, is known to immortalize human diploid fibroblast by soaking up cellular RB and p53, but its frequency is extremely low. Additional genetic alteration... -
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- The effects of transferring tumor suppressor gene p16INK4A to p16INK4A-deleted cancer cells
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Lee KY, Yoo CG, Han SK, Shim YS, Kim YW
- KMID: 759084
- Korean J Intern Med.
- 1999 Jan;14(1):53-58.
OBJECTIVES: p16 is known to be an important tumor suppressor gene and is also called MTS1 (multiple tumor suppressive gene 1). Especially in the case of non-small cell... -
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- Alterations of proliferative and differentiation potentials of human embryonic stem cells during long-term culture
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Park YB, Kim YY, Oh SK, Chung SG, Ku SY, Kim SH, Choi YM, Moon SY
- KMID: 1103593
- Exp Mol Med.
- 2008 Feb;40(1):98-108.
- doi: 10.3858/emm.2008.40.1.98
Human embryonic stem cells (hESCs) are considered to be able to stably maintain their characteristics in vitro for prolonged periods, but we had previously encountered changes in proliferative ability and... -
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