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Although it has been suggested that kinesin family member 14 (KIF14) has oncogenic potential in various cancers, including hepatocellular carcinoma (HCC), the molecular mechanism of this potential remains unknown. We...
Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY
KMID: 1093610
Exp Mol Med.
2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)...
Epidemiological studies have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the incidence of colon cancer. In addition, NSAIDs reduce the number and size of polyps in patients with familial adenomatous...
p21 protein has been reported to be a critical downstream effector of p53 and a
potent inhibitor of cyclin-dependent kinases. Thus, the p21 gene is thought to
play a...